A global accounting of medically significant scorpions: Epidemiology, major toxins, and comparative resources in harmless counterparts
Scorpions are an ancient and diverse venomous lineage, with over 2200 currently
recognized species. Only a small fraction of scorpion species are considered harmful to …
recognized species. Only a small fraction of scorpion species are considered harmful to …
[HTML][HTML] Epidemiological review of scorpion envenomation in Iran
This epidemiological review was carried out to display the magnitude and the geographic
distribution of scorpion envenomation in Iran with focus on the southwestern region of Iran …
distribution of scorpion envenomation in Iran with focus on the southwestern region of Iran …
A review of epidemiological, clinical and in vitro physiological studies of envenomation by the scorpion Hemiscorpius lepturus (Hemiscorpiidae) in Iran
Many of the published accounts of envenomation by Hemiscorpius lepturus (H. lepturus) are
in a form that makes it difficult for non Farsi readers to access. The purpose of this review is …
in a form that makes it difficult for non Farsi readers to access. The purpose of this review is …
Scorpion Toxins Specific for Potassium (K+) Channels: A Historical Overview of Peptide Bioengineering
ZL Bergeron, JP Bingham - Toxins, 2012 - mdpi.com
Scorpion toxins have been central to the investigation and understanding of the
physiological role of potassium (K+) channels and their expansive function in membrane …
physiological role of potassium (K+) channels and their expansive function in membrane …
Scorpion venom (Odontobuthus doriae) induces apoptosis by depolarization of mitochondria and reduces S-phase population in human breast cancer cells (MCF-7)
Venom of some species of scorpions induces apoptosis and arrests proliferation in cancer
cells. This is an important property that can be harnessed and can lead to isolation of …
cells. This is an important property that can be harnessed and can lead to isolation of …
Scorpion toxin peptide action at the ion channel subunit level
DM Housley, GD Housley, MJ Liddell, EA Jennings - Neuropharmacology, 2017 - Elsevier
This review categorizes functionally validated actions of defined scorpion toxin (SCTX)
neuropeptides across ion channel subclasses, highlighting key trends in this rapidly …
neuropeptides across ion channel subclasses, highlighting key trends in this rapidly …
Molecular diversity and functional evolution of scorpion potassium channel toxins
S Zhu, S Peigneur, B Gao, L Luo, D Jin, Y Zhao… - Molecular & Cellular …, 2011 - ASBMB
Scorpion toxins affecting K+ channels (KTxs) represent important pharmacological tools and
potential drug candidates. Here, we report molecular characterization of seven new KTxs in …
potential drug candidates. Here, we report molecular characterization of seven new KTxs in …
KV1. 2 channel-specific blocker from Mesobuthus eupeus scorpion venom: Structural basis of selectivity
AI Kuzmenkov, OV Nekrasova, S Peigneur… - …, 2018 - Elsevier
Scorpion venom is an unmatched source of selective high-affinity ligands of potassium
channels. There is a high demand for such compounds to identify and manipulate the …
channels. There is a high demand for such compounds to identify and manipulate the …
Isolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels
CH Thompson, PR Olivetti, MD Fuller… - Journal of biological …, 2009 - ASBMB
The ClC protein family includes voltage-gated chloride channels and chloride/proton
exchangers. In eukaryotes, ClC proteins regulate membrane potential of excitable cells …
exchangers. In eukaryotes, ClC proteins regulate membrane potential of excitable cells …
Mass spectrometric analysis of Odonthobuthus Doriae scorpion venom and its non-neutralized fractions after interaction with commercial antivenom
It is believed that antivenoms play a crucial role in neutralizing venoms. However,
uncontrolled clinical effects appear in patients stung by scorpions after the injection of …
uncontrolled clinical effects appear in patients stung by scorpions after the injection of …