Heart failure with preserved ejection fraction in perspective
MA Pfeffer, AM Shah, BA Borlaug - Circulation research, 2019 - Am Heart Assoc
Approximately half of the patients with signs and symptoms of heart failure have a left
ventricular ejection fraction that is not markedly abnormal. Despite the historically initial …
ventricular ejection fraction that is not markedly abnormal. Despite the historically initial …
Heart failure with preserved ejection fraction: from mechanisms to therapies
This review aims to provide a translational perspective on recent developments in heart
failure with preserved ejection fraction (HFpEF), linking mechanistic insights to potential …
failure with preserved ejection fraction (HFpEF), linking mechanistic insights to potential …
Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management. Position statement on behalf of the Heart Failure …
TM Gorter, DJ van Veldhuisen… - European journal of …, 2018 - Wiley Online Library
There is an unmet need for effective treatment strategies to reduce morbidity and mortality in
patients with heart failure with preserved ejection fraction (HFpEF). Until recently, attention in …
patients with heart failure with preserved ejection fraction (HFpEF). Until recently, attention in …
Myocardial microvascular inflammatory endothelial activation in heart failure with preserved ejection fraction
C Franssen, S Chen, A Unger, HI Korkmaz… - JACC: Heart Failure, 2016 - jacc.org
Objectives: The present study investigated whether systemic, low-grade inflammation of
metabolic risk contributed to diastolic left ventricular (LV) dysfunction and heart failure with …
metabolic risk contributed to diastolic left ventricular (LV) dysfunction and heart failure with …
Right ventricular dysfunction in heart failure with preserved ejection fraction: a systematic review and meta‐analysis
TM Gorter, ES Hoendermis… - European journal of …, 2016 - Wiley Online Library
Aims Right ventricular (RV) dysfunction and pulmonary hypertension (PH) are increasingly
recognized in heart failure with preserved ejection fraction (HFpEF). The prevalence and …
recognized in heart failure with preserved ejection fraction (HFpEF). The prevalence and …
[HTML][HTML] Epidemiology and pathogenesis of heart failure with preserved ejection fraction
N Nair - Reviews in cardiovascular medicine, 2020 - imrpress.com
Heart failure (HF) is a complex syndrome that affects approximately 6.5 million adults in the
United States. About half of the 6.5 million adults with HF are estimated to be individuals with …
United States. About half of the 6.5 million adults with HF are estimated to be individuals with …
Exercise unmasks distinct pathophysiologic features in heart failure with preserved ejection fraction and pulmonary vascular disease
TM Gorter, M Obokata, YNV Reddy… - European heart …, 2018 - academic.oup.com
Aims Pulmonary hypertension (PH) and pulmonary vascular disease (PVD) are common
and associated with adverse outcomes in heart failure with preserved ejection fraction …
and associated with adverse outcomes in heart failure with preserved ejection fraction …
Endothelial dysfunction in chronic heart failure: assessment, findings, significance, and potential therapeutic targets
MM Alem - International Journal of Molecular Sciences, 2019 - mdpi.com
Chronic heart failure (CHF) is a complex syndrome that results from structural and functional
disturbances that affect the ability of the heart to supply oxygen to tissues. It largely affects …
disturbances that affect the ability of the heart to supply oxygen to tissues. It largely affects …
The molecular mechanisms associated with the physiological responses to inflammation and oxidative stress in cardiovascular diseases
S Zhazykbayeva, S Pabel, A Mügge, S Sossalla… - Biophysical …, 2020 - Springer
The complex physiological signal transduction networks that respond to the dual challenges
of inflammatory and oxidative stress are major factors that promote the development of …
of inflammatory and oxidative stress are major factors that promote the development of …
Cardiac endothelium–myocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection fraction
Heart failure (HF) is an important global health problem with great socioeconomic burden.
Outcomes remain sub-optimal. Endothelium–cardiomyocyte interactions play essential roles …
Outcomes remain sub-optimal. Endothelium–cardiomyocyte interactions play essential roles …