The idiopathic inflammatory myopathies are characterized by muscle weakness, skin
disease and internal organ involvement. Autoimmunity is known to have a role in myositis …

The idiopathic inflammatory myopathies (IIMs; also known as myositis) are a heterogeneous
group of disorders in which a common feature is chronic inflammation of skeletal muscle …

Objective To develop and validate new classification criteria for adult and juvenile idiopathic
inflammatory myopathies (IIM) and their major subgroups. Methods Candidate variables …

Importance Idiopathic inflammatory myopathies are heterogeneous in their pathophysiologic
features and prognosis. The emergence of myositis-specific autoantibodies suggests that …

Objectives To determine prevalence and co-existence of myositis specific autoantibodies
(MSAs) and myositis associated autoantibodies (MAAs) and associated clinical …

Autoantibodies specific for idiopathic inflammatory myopathy (myositis-specific
autoantibodies (MSAs)) are clinically useful biomarkers to help the diagnosis of …

The discovery of novel autoantigen systems related to idiopathic inflammatory myopathies
(collectively referred to as myositis) in adults and children has had major implications for the …

Objective To assess the safety and efficacy of rituximab in a randomized, double‐blind,
placebo‐phase trial in adult and pediatric myositis patients. Methods Adults with refractory …

The inflammatory myopathies, commonly described as idiopathic, are the largest group of
acquired and potentially treatable myopathies. On the basis of unique clinical …

BACKGROUND: Dermatomyositis (DM) is a multisystem autoimmune disease, in which
serologic evidence of immune responses to disease-specific antigenic targets is found in …