Review of retrospective dosimetry techniques for external ionising radiation exposures

EA Ainsbury, E Bakhanova… - Radiation protection …, 2011 - academic.oup.com
The current focus on networking and mutual assistance in the management of radiation
accidents or incidents has demonstrated the importance of a joined-up approach in physical …

Use of biomarkers for assessing radiation injury and efficacy of countermeasures

VK Singh, VL Newman, PLP Romaine… - Expert review of …, 2016 - Taylor & Francis
Several candidate drugs for acute radiation syndrome (ARS) have been identified that have
low toxicity and significant radioprotective and radiomitigative efficacy. Inasmuch as …

Assessment of biodosimetry methods for a mass-casualty radiological incident: medical response and management considerations

JM Sullivan, PGS Prasanna, MB Grace… - Health …, 2013 - journals.lww.com
Following a mass-casualty nuclear disaster, effective medical triage has the potential to save
tens of thousands of lives. In order to best use the available scarce resources, there is an …

Identification of sensitive serum microRNA biomarkers for radiation biodosimetry

NK Jacob, JV Cooley, TN Yee, J Jacob, H Alder… - PloS one, 2013 - journals.plos.org
Exposure to ionizing radiation through environmental, occupational or a nuclear reactor
accident such as the recent Fukushima Daiichi incident often results in major consequences …

The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates

CE Redon, AJ Nakamura, K Gouliaeva, A Rahman… - PloS one, 2010 - journals.plos.org
Background There is a crucial shortage of methods capable of determining the extent of
accidental exposures of human beings to ionizing radiation. However, knowledge of …

Prediction of In Vivo Radiation Dose Status in Radiotherapy Patients using Ex Vivo and In Vivo Gene Expression Signatures

S Paul, CA Barker, HC Turner, A McLane… - Radiation …, 2011 - meridian.allenpress.com
After a large-scale nuclear accident or an attack with an improvised nuclear device, rapid
biodosimetry would be needed for triage. As a possible means to address this need, we …

SERS-based lateral flow assay for quantitative detection of C-reactive protein as an early bio-indicator of a radiation-induced inflammatory response in nonhuman …

Z Rong, R Xiao, S Xing, G Xiong, Z Yu, L Wang, X Jia… - Analyst, 2018 - pubs.rsc.org
In accidental irradiation situations, rapid in-field evaluation of acute radiation syndrome is
critical for effective triage and timely medical treatment of irradiated individuals. A surface …

Early molecular markers for retrospective biodosimetry and prediction of acute health effects

M Abend, WF Blakely, P Ostheim… - Journal of …, 2022 - iopscience.iop.org
Radiation-induced biological changes occurring within hours and days after irradiation can
be potentially used for either exposure reconstruction (retrospective dosimetry) or the …

Nonhuman primates as models for the discovery and development of radiation countermeasures

VK Singh, AO Olabisi - Expert opinion on drug discovery, 2017 - Taylor & Francis
Introduction: Despite significant scientific advances over the past six decades toward the
development of safe and effective radiation countermeasures for humans using animal …

State-of-the-art advances in radiation biodosimetry for mass casualty events involving radiation exposure

M Sproull, K Camphausen - Radiation research, 2016 - meridian.allenpress.com
With the possibility of large-scale terrorist attacks around the world, the need for modeling
and development of new medical countermeasures for potential future chemical, biological …