Emerging behavioral and neuroimaging biomarkers for early and accurate characterization of autism spectrum disorders: a systematic review

CS Hiremath, KJV Sagar, BK Yamini… - Translational …, 2021 - nature.com
The possibility of early treatment and a better outcome is the direct product of early
identification and characterization of any pathological condition. Autism spectrum disorder …

Altered motor learning and coordination in mouse models of autism spectrum disorder

KR Cording, HS Bateup - Frontiers in cellular neuroscience, 2023 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with increasing
prevalence. Over 1,000 risk genes have now been implicated in ASD, suggesting diverse …

Adenosine mediates the amelioration of social novelty deficits during rhythmic light treatment of 16p11. 2 deletion female mice

J Ju, X Li, Y Pan, J Du, X Yang, S Men, B Liu… - Molecular …, 2024 - nature.com
Non-invasive brain stimulation therapy for autism spectrum disorder (ASD) has shown
beneficial effects. Recently, we and others demonstrated that visual sensory stimulation …

[HTML][HTML] Sleep disturbances in autism spectrum disorder: Animal models, neural mechanisms, and therapeutics

JJ Maurer, A Choi, I An, N Sathi, S Chung - Neurobiology of Sleep and …, 2023 - Elsevier
Sleep is crucial for brain development. Sleep disturbances are prevalent in children with
autism spectrum disorder (ASD). Strikingly, these sleep problems are positively correlated …

Dissecting 16p11. 2 hemi-deletion to study sex-specific striatal phenotypes of neurodevelopmental disorders

J Kim, Y Vanrobaeys, B Kelvington, Z Peterson… - Molecular …, 2024 - nature.com
Neurodevelopmental disorders (NDDs) are polygenic in nature and copy number variants
(CNVs) are ideal candidates to study the nature of this polygenic risk. The disruption of …

[HTML][HTML] Sex-specific stress-related behavioral phenotypes and central amygdala dysfunction in a mouse model of 16p11. 2 microdeletion

J Giovanniello, S Ahrens, K Yu, B Li - Biological Psychiatry Global Open …, 2021 - Elsevier
Background Substantial evidence indicates that a microdeletion on human chromosome
16p11. 2 is linked to neurodevelopmental disorders, including autism spectrum disorder …

Tactile sensory processing deficits in genetic mouse models of autism spectrum disorder

M Falcão, P Monteiro, L Jacinto - Journal of Neurochemistry, 2024 - Wiley Online Library
Altered sensory processing is a common feature in autism spectrum disorder (ASD), as
recognized in the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5). Although …

[HTML][HTML] Towards Preclinical Validation of Arbaclofen (R-baclofen) Treatment for 16p11. 2 Deletion Syndrome

BB Gundersen, WT O'Brien, MD Schaffler, MN Schultz… - bioRxiv, 2023 - ncbi.nlm.nih.gov
A microdeletion on human chromosome 16p11. 2 is one of the most common copy number
variants associated with autism spectrum disorder and other neurodevelopmental …

[HTML][HTML] Circuit mechanism underlying fragmented sleep and memory deficits in 16p11. 2 deletion mouse model of autism

A Choi, J Smith, Y Wang, H Shin, B Kim, A Wiest… - Research …, 2023 - ncbi.nlm.nih.gov
Sleep disturbances are prevalent in children with autism spectrum disorder (ASD) and have
a major impact on the quality of life. Strikingly, sleep problems are positively correlated with …

ACSS2 contributes to transcriptional regulation in Cajal-Retzius cells in a mouse model of Alzheimer's disease

G Egervari, DC Alexander, G Donahue, H Huang… - bioRxiv, 2024 - biorxiv.org
Dysregulation of histone acetylation in the brain has emerged as a major contributor to
human Alzheimer's disease (AD). The mechanisms by which these protective or risk …