Emerging behavioral and neuroimaging biomarkers for early and accurate characterization of autism spectrum disorders: a systematic review
The possibility of early treatment and a better outcome is the direct product of early
identification and characterization of any pathological condition. Autism spectrum disorder …
identification and characterization of any pathological condition. Autism spectrum disorder …
Altered motor learning and coordination in mouse models of autism spectrum disorder
KR Cording, HS Bateup - Frontiers in cellular neuroscience, 2023 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with increasing
prevalence. Over 1,000 risk genes have now been implicated in ASD, suggesting diverse …
prevalence. Over 1,000 risk genes have now been implicated in ASD, suggesting diverse …
Adenosine mediates the amelioration of social novelty deficits during rhythmic light treatment of 16p11. 2 deletion female mice
Non-invasive brain stimulation therapy for autism spectrum disorder (ASD) has shown
beneficial effects. Recently, we and others demonstrated that visual sensory stimulation …
beneficial effects. Recently, we and others demonstrated that visual sensory stimulation …
[HTML][HTML] Sleep disturbances in autism spectrum disorder: Animal models, neural mechanisms, and therapeutics
JJ Maurer, A Choi, I An, N Sathi, S Chung - Neurobiology of Sleep and …, 2023 - Elsevier
Sleep is crucial for brain development. Sleep disturbances are prevalent in children with
autism spectrum disorder (ASD). Strikingly, these sleep problems are positively correlated …
autism spectrum disorder (ASD). Strikingly, these sleep problems are positively correlated …
Dissecting 16p11. 2 hemi-deletion to study sex-specific striatal phenotypes of neurodevelopmental disorders
Neurodevelopmental disorders (NDDs) are polygenic in nature and copy number variants
(CNVs) are ideal candidates to study the nature of this polygenic risk. The disruption of …
(CNVs) are ideal candidates to study the nature of this polygenic risk. The disruption of …
[HTML][HTML] Sex-specific stress-related behavioral phenotypes and central amygdala dysfunction in a mouse model of 16p11. 2 microdeletion
Background Substantial evidence indicates that a microdeletion on human chromosome
16p11. 2 is linked to neurodevelopmental disorders, including autism spectrum disorder …
16p11. 2 is linked to neurodevelopmental disorders, including autism spectrum disorder …
Tactile sensory processing deficits in genetic mouse models of autism spectrum disorder
M Falcão, P Monteiro, L Jacinto - Journal of Neurochemistry, 2024 - Wiley Online Library
Altered sensory processing is a common feature in autism spectrum disorder (ASD), as
recognized in the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5). Although …
recognized in the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5). Although …
[HTML][HTML] Towards Preclinical Validation of Arbaclofen (R-baclofen) Treatment for 16p11. 2 Deletion Syndrome
BB Gundersen, WT O'Brien, MD Schaffler, MN Schultz… - bioRxiv, 2023 - ncbi.nlm.nih.gov
A microdeletion on human chromosome 16p11. 2 is one of the most common copy number
variants associated with autism spectrum disorder and other neurodevelopmental …
variants associated with autism spectrum disorder and other neurodevelopmental …
[HTML][HTML] Circuit mechanism underlying fragmented sleep and memory deficits in 16p11. 2 deletion mouse model of autism
A Choi, J Smith, Y Wang, H Shin, B Kim, A Wiest… - Research …, 2023 - ncbi.nlm.nih.gov
Sleep disturbances are prevalent in children with autism spectrum disorder (ASD) and have
a major impact on the quality of life. Strikingly, sleep problems are positively correlated with …
a major impact on the quality of life. Strikingly, sleep problems are positively correlated with …
ACSS2 contributes to transcriptional regulation in Cajal-Retzius cells in a mouse model of Alzheimer's disease
G Egervari, DC Alexander, G Donahue, H Huang… - bioRxiv, 2024 - biorxiv.org
Dysregulation of histone acetylation in the brain has emerged as a major contributor to
human Alzheimer's disease (AD). The mechanisms by which these protective or risk …
human Alzheimer's disease (AD). The mechanisms by which these protective or risk …