The developing eye‐antennal disc of Drosophila melanogaster has been studied for more
than a century, and it has been used as a model system to study diverse processes, such as …

Mutations in glycosylation pathways, such as N-linked glycosylation, O-linked glycosylation,
and GPI anchor synthesis, lead to Congenital Disorders of Glycosylation (CDG). CDG …

Partial loss-of-function mutations in glycosylation pathways underlie a set of rare diseases
called Congenital Disorders of Glycosylation (CDGs). In particular, DPAGT1-CDG is caused …

Paired box 6 (Pax6) is considered to be the master control gene for eye development in all
seeing animals studied so far. In vertebrates, it is required not only for lens/retina formation …

The transcription factor Pax6 is considered the master control gene for eye formation
because (1) it is present within the genomes and retina/lens of all animals with a visual …

DPAGT1-CDG is a Congenital Disorder of Glycosylation (CDG) that lacks effective therapies.
It is caused by mutations in the gene DPAGT1 which encodes the first enzyme in N-linked …

The eye-antennal disc of Drosophila is composed of three cell layers: a columnar epithelium
called the disc proper (DP); an overlying sheet of squamous cells called the peripodial …

How different cells and tissues commit to and determine their fates has been a central
question in developmental biology since the seminal embryological experiments conducted …

The metabolic enzymes that compose glycolysis, the citric acid cycle, and other pathways
within central carbon metabolism have emerged as key regulators of animal development …

Drosophila melanogaster head development represents a valuable process to study the
developmental control of various organs, such as the antennae, the dorsal ocelli and the …