Fullerenes in biology and medicine

E Castro, AH Garcia, G Zavala… - Journal of Materials …, 2017 - pubs.rsc.org
Fullerenes and related carbon based derivatives have shown a growing relevance in
biology and medicine, mainly due to the unique electronic and structural properties that …

[HTML][HTML] Functionalized fullerenes and their applications in electrochemistry, solar cells, and nanoelectronics

M Paukov, C Kramberger, I Begichev, M Kharlamova… - Materials, 2023 - mdpi.com
Carbon-based nanomaterials have rapidly advanced over the last few decades. Fullerenes,
carbon nanotubes, graphene and its derivatives, graphene oxide, nanodiamonds, and …

Water-soluble fullerene derivatives as brain medicine: surface chemistry determines if they are neuroprotective and antitumor

FY Hsieh, AV Zhilenkov, II Voronov… - … Applied Materials & …, 2017 - ACS Publications
Delivering drugs to the central nervous system (CNS) is a major challenge in treating CNS-
related diseases. Nanoparticles that can cross blood–brain barrier (BBB) are potential tools …

[HTML][HTML] Progress in antiviral fullerene research

PY Xu, XQ Li, WG Chen, LL Deng, YZ Tan, Q Zhang… - Nanomaterials, 2022 - mdpi.com
Unlike traditional small molecule drugs, fullerene is an all-carbon nanomolecule with a
spherical cage structure. Fullerene exhibits high levels of antiviral activity, inhibiting virus …

Toward understanding the antitumor effects of water-soluble fullerene derivatives on lung cancer cells: Apoptosis or autophagy pathways?

CW Wong, AV Zhilenkov, OA Kraevaya… - Journal of Medicinal …, 2019 - ACS Publications
Here we report the synthesis and investigation of anticancer effects of a series of water-
soluble fullerene derivatives bearing amino acid (F1–F7) and thioacid (F8–F10) residues …

[HTML][HTML] A zeta potential value determines the aggregate's size of penta-substituted [60] fullerene derivatives in aqueous suspension whereas positive charge is …

DG Deryabin, LV Efremova, AS Vasilchenko… - Journal of …, 2015 - Springer
Background The cause–effect relationships between physicochemical properties of
amphiphilic [60] fullerene derivatives and their toxicity against bacterial cells have not yet …

Regioselective Synthesis and Crystallographic Characterization of Nontethered cis-1 and cis-2 Bis(benzofuro)[60]fullerene Derivatives

L Ding, B Jin, Z Guo, Y Zhao, J Chen, R Peng - Organic letters, 2019 - ACS Publications
The regioselective synthesis of fullerene bis-adducts remains challenging because it
produces large amounts of regioisomers. Novel nontethered cis-1 and cis-2 bis …

Synthesis of different types of alkoxy fullerene derivatives from chlorofullerene C 60 Cl 6

EA Khakina, AK Ol'ga, ML Popova… - Organic & …, 2017 - pubs.rsc.org
We report novel synthetic routes for facile preparation of highly functionalized fullerene
derivatives C60 (OR) 5X (X= H, Cl, Br), C60 (OR) 4O and C60 (OR) 2 from chlorofullerene …

Novel pyridinium-type fullerene derivatives as multitargeting inhibitors of HIV-1 reverse transcriptase, HIV-1 protease, and HCV NS5B polymerase

T Kobayashi, T Yasuno, K Takahashi… - Bioorganic & Medicinal …, 2021 - Elsevier
In the present study, we newly synthesized four types of novel fullerene derivatives:
pyridinium/ethyl ester-type derivatives 3b− 3l, pyridinium/carboxylic acid-type derivatives 4a …

Arbuzov chemistry with chlorofullerene C60Cl6: a powerful method for selective synthesis of highly functionalized [60] fullerene derivatives

AA Yurkova, EA Khakina, SI Troyanov… - Chemical …, 2012 - pubs.rsc.org
We report Arbuzov-type reactions of chlorofullerene C60Cl6 with trialkyl phosphites
producing highly functionalized fullerene derivatives C60 [P (O)(OR) 2] 5H with high yields …