The conjugation of metal-based scaffolds to peptides, proteins, or antibodies allows the
systemic targeting of these payloads to specific locations in the body, such as target …

Protein metalation is a process that determines the formation of adducts upon reaction of
metal compounds with proteins. Protein metalation plays a crucial role in different fields …

Combination therapy targeting both tumor growth and vascularization is considered to be a
cornerstone for colorectal carcinomas (CRC) treatment. However, the major obstacles of …

The development of bifunctional platinum complexes with the ability to interact with DNA via
different binding modes is of interest in anticancer metallodrug research. Therefore, we …

Herein, we studied the interaction of bovine pancreatic ribonuclease (RNase A) with [VIVO
(8-HQ) 2]–a promising antitrypanosomal, antituberculosis, and antitumor vanadium complex …

Supramolecular structure and properties of deep eutectic solvents (DESs) are known to be
highly affected by the addition of water, and their use as solvents for poorly water-soluble …

Metal complexes can be considered a “paradigm of promiscuity” when it comes to their
interactions with proteins. They often form adducts with a variety of donor atoms in an …

The structure and the reactivity of four half-sandwich metal complexes of RuII, OsII, RhIII, and
IrIII were investigated by means of density functional theory approaches. These piano-stool …

Various half-sandwich ruthenium (II) arene complexes and rhodium (III) arene complexes
have been intensively investigated due to their prominent anticancer activity. The interaction …

N-Heterocyclic carbene (NHC) ligands are widely investigated in medicinal inorganic
chemistry. Here, we report the preparation and characterization of a series of half-sandwich …