COVID-19 prophylaxis efforts based on natural antiviral plant extracts and their compounds

O Sytar, M Brestic, S Hajihashemi, M Skalicky, J Kubeš… - Molecules, 2021 - mdpi.com
During the time of the novel coronavirus disease 2019 (COVID-19) pandemic, it has been
crucial to search for novel antiviral drugs from plants and well as other natural sources as …

Cannabidiol goes nuclear: The role of PPARγ

S Khosropoor, MS Alavi, L Etemad, A Roohbakhsh - Phytomedicine, 2023 - Elsevier
Background Cannabidiol (CBD) is one of the main phytocannabinoids found in Cannabis
sativa. In contrast to Δ9-tetrahydrocannabinol, it has a low affinity for cannabinoid receptors …

Cannabidiol for COVID-19 patients with mild to moderate symptoms (CANDIDATE Study): a randomized, double-blind, placebo-controlled clinical trial

JAS Crippa, JC Pacheco, AW Zuardi… - Cannabis and …, 2022 - liebertpub.com
Importance: Owing to its anti-inflammatory properties and antiviral “in vitro” effect against
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), cannabidiol (CBD) has …

Antimicrobial and Antiviral (SARS-CoV-2) Potential of Cannabinoids and Cannabis sativa: A Comprehensive Review

MS Mahmud, MS Hossain, ATMF Ahmed, MZ Islam… - Molecules, 2021 - mdpi.com
Antimicrobial resistance has emerged as a global health crisis and, therefore, new drug
discovery is a paramount need. Cannabis sativa contains hundreds of chemical constituents …

Effects of cannabidiol on innate immunity: experimental evidence and clinical relevance

S Martini, A Gemma, M Ferrari, M Cosentino… - International Journal of …, 2023 - mdpi.com
Cannabidiol (CBD) is the main non-psychotropic cannabinoid derived from cannabis
(Cannabis sativa L., fam. Cannabaceae). CBD has received approval by the Food and Drug …

Cannabinoids and the coronavirus

KP Hill - Cannabis and cannabinoid research, 2020 - liebertpub.com
These are uncertain times as we attempt to manage our lives during the Coronavirus Covid-
19 pandemic. It is not surprising, as possible treatments for Covid-19 are discussed, that …

Antiviral activity of cannabidiolic acid and its methyl ester against SARS-CoV-2

M Tamburello, S Salamone, L Anceschi… - Journal of Natural …, 2023 - ACS Publications
In the present study, the antiviral activity of cannabinoids isolated from Cannabis sativa L.
was assessed in vitro against a panel of SARS-CoV-2 variants, indicating cannabidiolic acid …

Identification of SARS-CoV-2 Main protease inhibitors from a library of minor cannabinoids by biochemical inhibition assay and surface plasmon resonance …

C Liu, T Puopolo, H Li, A Cai, NP Seeram, H Ma - Molecules, 2022 - mdpi.com
The replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
mediated by its main protease (Mpro), which is a plausible therapeutic target for coronavirus …

Cannabidiol and SARS-CoV-2 infection

A Vallée - Frontiers in Immunology, 2022 - frontiersin.org
Cannabidiol (CBD) can prevent the inflammatory response of SARS-CoV-2 spike protein in
Caco-2-cells. This action is coupled with the inhibition of IL-1beta, IL-6, IL-18, and TNF …

Cross-sectional associations between lifetime use of psychedelic drugs and psychometric measures during the COVID-19 confinement: a transcultural study

D Révész, G Ona, GN Rossi, JM Rocha… - Frontiers in …, 2021 - frontiersin.org
Background: One of the main public health strategies adopted at the beginning of the COVID-
19 pandemic consisted of implementing strict lockdowns to stop the transmission of the …