Structural and dynamic mechanisms for coupled folding and tRNA recognition of a translational T-box riboswitch
X Niu, Z Xu, Y Zhang, X Zuo, C Chen, X Fang - Nature Communications, 2023 - nature.com
T-box riboswitches are unique riboregulators where gene regulation is mediated through
interactions between two highly structured RNAs. Despite extensive structural insights, how …
interactions between two highly structured RNAs. Despite extensive structural insights, how …
Translational T-box riboswitches bind tRNA by modulating conformational flexibility
T-box riboswitches are noncoding RNA elements involved in genetic regulation of most
Gram-positive bacteria. They regulate amino acid metabolism by assessing the …
Gram-positive bacteria. They regulate amino acid metabolism by assessing the …
Structural basis of NEAT1 lncRNA maturation and menRNA instability
I Skeparnias, J Zhang - Nature Structural & Molecular Biology, 2024 - nature.com
NEAT1 long noncoding RNA orchestrates paraspeckle assembly and impacts
tumorigenesis, fertility and immunity. Its maturation requires RNase P cleavage yielding an …
tumorigenesis, fertility and immunity. Its maturation requires RNase P cleavage yielding an …
Structural idiosyncrasies of glycyl T-box riboswitches among pathogenic bacteria
T-box riboswitches are widespread bacterial regulatory noncoding RNAs that directly
interact with tRNAs and switch conformations to regulate the transcription or translation of …
interact with tRNAs and switch conformations to regulate the transcription or translation of …
[HTML][HTML] RNA folding kinetics control riboswitch sensitivity in vivo
DZ Bushhouse, J Fu, JB Lucks - bioRxiv, 2024 - ncbi.nlm.nih.gov
Riboswitches are ligand-responsive gene-regulatory RNA elements that perform key roles in
maintaining cellular homeostasis. Understanding how riboswitch sensitivity is controlled is …
maintaining cellular homeostasis. Understanding how riboswitch sensitivity is controlled is …
Recognition of the tRNA structure: Everything everywhere but not all at once
J Zhang - Cell Chemical Biology, 2023 - cell.com
Summary tRNAs are among the most abundant and essential biomolecules in cells. These
spontaneously folding, extensively structured yet conformationally flexible anionic polymers …
spontaneously folding, extensively structured yet conformationally flexible anionic polymers …