Frontiers in the treatment of glioblastoma: Past, present and emerging
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …
research over the last several decades, the survival rates for GBM have not improved and …
The role of imaging in targeted delivery of nanomedicine for cancer therapy
P Li, D Wang, J Hu, X Yang - Advanced Drug Delivery Reviews, 2022 - Elsevier
Nanomedicines overcome the pharmacokinetic limitations of traditional drug formulations
and have promising prospect in cancer treatment. However, nanomedicine delivery in vivo is …
and have promising prospect in cancer treatment. However, nanomedicine delivery in vivo is …
Nanotechnology and nanocarrier-based drug delivery as the potential therapeutic strategy for glioblastoma multiforme: An update
JF Hsu, SM Chu, CC Liao, CJ Wang, YS Wang, MY Lai… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) are among the most lethal tumors. The
highly invasive nature and presence of GBM stem cells, as well as the blood brain barrier …
highly invasive nature and presence of GBM stem cells, as well as the blood brain barrier …
Recent advances in the therapeutic strategies of glioblastoma multiforme
Glioblastoma multiforme (GBM) is one of the most common, most formidable, and deadliest
malignant types of primary astrocytoma with a poor prognosis. At present, the standard of …
malignant types of primary astrocytoma with a poor prognosis. At present, the standard of …
Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application
L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …
Delivering the promise of gene therapy with nanomedicines in treating central nervous system diseases
Abstract Central Nervous System (CNS) diseases, such as Alzheimer's diseases (AD),
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …
Transferrin receptor-targeted nanocarriers: overcoming barriers to treat glioblastoma
MJ Ramalho, JA Loureiro, MAN Coelho, MC Pereira - Pharmaceutics, 2022 - mdpi.com
Glioblastoma multiforme (GBM) is the most common and lethal type of brain tumor, and the
clinically available approaches for its treatment are not curative. Despite the intensive …
clinically available approaches for its treatment are not curative. Despite the intensive …
Quantifying intracellular nanoparticle distributions with three-dimensional super-resolution microscopy
Super-resolution microscopy can transform our understanding of nanoparticle–cell
interactions. Here, we established a super-resolution imaging technology to visualize …
interactions. Here, we established a super-resolution imaging technology to visualize …
[HTML][HTML] Nanoparticle-based drug delivery across the blood-brain barrier for treating malignant brain glioma
In spite of substantial progress made in the standard treatment and ancillary therapies that
include concurrent chemotherapy, radiotherapy, and surgery, malignant brain tumors …
include concurrent chemotherapy, radiotherapy, and surgery, malignant brain tumors …
Multimodal decorations of mesoporous silica nanoparticles for improved cancer therapy
The presence of leaky vasculature and the lack of lymphatic drainage of small structures by
the solid tumors formulate nanoparticles as promising delivery vehicles in cancer therapy. In …
the solid tumors formulate nanoparticles as promising delivery vehicles in cancer therapy. In …