Frontiers in the treatment of glioblastoma: Past, present and emerging

TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed… - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

The role of imaging in targeted delivery of nanomedicine for cancer therapy

P Li, D Wang, J Hu, X Yang - Advanced Drug Delivery Reviews, 2022 - Elsevier
Nanomedicines overcome the pharmacokinetic limitations of traditional drug formulations
and have promising prospect in cancer treatment. However, nanomedicine delivery in vivo is …

Nanotechnology and nanocarrier-based drug delivery as the potential therapeutic strategy for glioblastoma multiforme: An update

JF Hsu, SM Chu, CC Liao, CJ Wang, YS Wang, MY Lai… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) are among the most lethal tumors. The
highly invasive nature and presence of GBM stem cells, as well as the blood brain barrier …

Recent advances in the therapeutic strategies of glioblastoma multiforme

AF Aldoghachi, AF Aldoghachi, K Breyne, KH Ling… - Neuroscience, 2022 - Elsevier
Glioblastoma multiforme (GBM) is one of the most common, most formidable, and deadliest
malignant types of primary astrocytoma with a poor prognosis. At present, the standard of …

Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application

L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …

Delivering the promise of gene therapy with nanomedicines in treating central nervous system diseases

M Luo, LKC Lee, B Peng, CHJ Choi… - Advanced …, 2022 - Wiley Online Library
Abstract Central Nervous System (CNS) diseases, such as Alzheimer's diseases (AD),
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …

Transferrin receptor-targeted nanocarriers: overcoming barriers to treat glioblastoma

MJ Ramalho, JA Loureiro, MAN Coelho, MC Pereira - Pharmaceutics, 2022 - mdpi.com
Glioblastoma multiforme (GBM) is the most common and lethal type of brain tumor, and the
clinically available approaches for its treatment are not curative. Despite the intensive …

Quantifying intracellular nanoparticle distributions with three-dimensional super-resolution microscopy

V Sheth, X Chen, EM Mettenbrink, W Yang, MA Jones… - ACS …, 2023 - ACS Publications
Super-resolution microscopy can transform our understanding of nanoparticle–cell
interactions. Here, we established a super-resolution imaging technology to visualize …

[HTML][HTML] Nanoparticle-based drug delivery across the blood-brain barrier for treating malignant brain glioma

V Kurawattimath, B Wilson, KM Geetha - OpenNano, 2023 - Elsevier
In spite of substantial progress made in the standard treatment and ancillary therapies that
include concurrent chemotherapy, radiotherapy, and surgery, malignant brain tumors …

Multimodal decorations of mesoporous silica nanoparticles for improved cancer therapy

S Barui, V Cauda - Pharmaceutics, 2020 - mdpi.com
The presence of leaky vasculature and the lack of lymphatic drainage of small structures by
the solid tumors formulate nanoparticles as promising delivery vehicles in cancer therapy. In …