Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage
degradation but also synovial membrane inflammation, osteophyte formation and …

Objective This study was design to examine the diagnostic performance of cartilage
oligomeric matrix protein (COMP), C-terminal cross-linking telopeptide of type II collagen …

The infrapatellar fat pad (IPFP) and synovium play essential roles in maintaining knee joint
homeostasis and in the progression of osteoarthritis (OA). The cellular and transcriptional …

Several lines of research indicate that osteoarthritis (OA) is not only a joint disorder
associated with mechanical stress and aging but also a 'metabolic syndrome'in which …

Background Osteoarthritis (OA) is a slowly developing and debilitating disease, and there
are no validated specific biomarkers for its early detection. To improve therapeutic …

The contribution of metabolic factors on the severity of osteoarthritis (OA) is not fully
appreciated. This study aimed to define the effects of hyper cholesterolemia on the …

Osteoarthritis (OA) imposes an increasing social burden due to global activity limitations,
especially among the aged. Links between circulating lipids and OA have been reported; …

Synovial fluid (SF) extracellular vesicles (EVs) play a pathogenic role in osteoarthritis (OA).
However, the surface markers, cell and tissue origins, and effectors of these EVs are largely …

Snakes of the genus Bothrops are responsible the most snakebites in the Brazil, causing a
diverse and complex pathophysiological condition. Bothrops erythromelas is the main …

Bothrops spp. is responsible for about 70% of snakebites in Brazil, causing a diverse and
complex pathophysiological condition. Bothrops leucurus is the main species of medical …