[HTML][HTML] Advances in circular RNA and its applications

X Zhao, Y Zhong, X Wang, J Shen… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Circular RNA (circRNA) is a novel endogenous non-coding RNA (ncRNA) that, like
microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, unlike traditional …

Circular RNA in cancer

VM Conn, AM Chinnaiyan, SJ Conn - Nature Reviews Cancer, 2024 - nature.com
Over the past decade, circular RNA (circRNA) research has evolved into a bona fide
research field shedding light on the functional consequence of this unique family of RNA …

Deep learning and ensemble deep learning for circRNA-RBP interaction prediction in the last decade: A review

D Lasantha, S Vidanagamachchi… - … Applications of Artificial …, 2023 - Elsevier
Circular ribonucleic acids (circRNAs) are widely expressed in cells and tissues and play vital
roles in cellular physiological processes. Their expressions are associated with …

Therapeutic and diagnostic applications of exosomal circRNAs in breast cancer

M Gopikrishnan, HM Ashour, G Pintus… - Functional & Integrative …, 2023 - Springer
Circular RNAs (circRNAs) are regulatory elements that are involved in orchestrating gene
expression and protein functions and are implicated in various biological processes …

Characterization of circular RNAs with advanced sequencing technologies in human complex diseases

H Ruan, PC Wang, L Han - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Circular RNAs (circRNAs) are one category of non‐coding RNAs that do not possess 5′
caps and 3′ free ends. Instead, they are derived in closed circle forms from pre‐mRNAs by …

A crosstalk between circular RNA, microRNA, and messenger RNA in the development of various brain cognitive disorders

L He, F Zhang, Y Zhu, M Lu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Patients with Alzheimer's disease (AD), Parkinson's disease (PD), traumatic brain injury
(TBI), stroke, and postoperative neurocognitive disorder (POND) are commonly faced with …

[HTML][HTML] Ferroptosis related genes participate in the pathogenesis of spinal cord injury via HIF-1 signaling pathway

H Dong, C Zhang, D Shi, X Xiao, X Chen, Y Zeng… - Brain Research …, 2023 - Elsevier
Background Spinal cord injury (SCI) is a crushing disease without a effective and specific
therapeutic strategy. Therefore, it is crucial to uncover underlying mechanism in order to …

The recent advancements in circRNA research: From biogenesis to therapeutic interventions

A Malviya, R Bhuyan - Pathology-Research and Practice, 2023 - Elsevier
Circular RNAs (circRNAs) belong to the genre of long non-coding RNAs that are formed by
special back-splicing events and are currently the molecule of interest for studies globally …

Roles of aging, circular RNAs, and RNA editing in the pathogenesis of amyotrophic lateral sclerosis: potential biomarkers and therapeutic targets

T Hosaka, H Tsuji, S Kwak - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is an incurable motor neuron disease caused by upper
and lower motor neuron death. Despite advances in our understanding of ALS …

ChromLoops: a comprehensive database for specific protein-mediated chromatin loops in diverse organisms

Q Zhou, S Cheng, S Zheng, Z Wang… - Nucleic Acids …, 2023 - academic.oup.com
Chromatin loops (or chromatin interactions) are important elements of chromatin structures.
Disruption of chromatin loops is associated with many diseases, such as cancer and …