Cardiovascular disease (CVD) is the leading cause of death in the United States and aging
is a major risk factor for CVD development. One of the major age-related arterial phenotypes …

Type 2 diabetes is one of the fastest growing public health problems worldwide resulting
from both environmental and genetic factors. It is characterized by the abnormal glucose and …

The aim of the present study was to analyze the action of metformin on short-term memory,
glial cell activation and neuroinflammation caused by experimental diabetic encephalopathy …

Experimental autoimmune encephalomyelitis (EAE) is a T cell-mediated autoimmune
disease of the CNS. Metformin is the most widely used drug for diabetes and mediates its …

Background and Purpose Endothelial dysfunction can be detected at an early stage in the
development of diabetes‐related microvascular disease and is associated with accelerated …

The AMP-activated protein kinase (AMPK) was initially identified as the kinase that
phosphorylates the 3-hydroxy 3-methylglutaryl coenzyme A reductase, the rate-limiting …

Diabetes mellitus is associated with deterioration of glycemic control and progressive
metabolic derangements. This study investigated the effect of honey as an adjunct to …

Alzheimer's disease (AD) is the most prevalent neurodegenerative amyloid disorder with
progressive deterioration of cognitive and memory skills. Despite many efforts, no decisive …

AMP-activated protein kinase (AMPK) is proposed to be a key regulator of cellular and
organismal metabolism and has reported vasculoprotective effects. In addition, many …

AMP-activated protein kinase (AMPK), a phylogenetically conserved serine/threonine
protein kinase, is a major regulator of cellular and whole-body energy homeostasis that …