Molecular Mechanisms and the Significance of Synonymous Mutations
P Oelschlaeger - Biomolecules, 2024 - mdpi.com
Synonymous mutations result from the degeneracy of the genetic code. Most amino acids
are encoded by two or more codons, and mutations that change a codon to another …
are encoded by two or more codons, and mutations that change a codon to another …
Role of polymorphisms on the recurrent pregnancy loss: A systematic review, meta-analysis and bioinformatic analysis
Recurrent miscarriage (RM) is a major reproductive health issue. RM is a multi-factorial
disease, and is affected by environmental, genetic, and epigenetic factors. Genetics has a …
disease, and is affected by environmental, genetic, and epigenetic factors. Genetics has a …
Targeted demethylation of the CDO1 promoter based on CRISPR system inhibits the malignant potential of breast cancer cells
J Yang, L Sun, XY Liu, C Huang, J Peng… - Clinical and …, 2023 - Wiley Online Library
Abstract Background Cysteine dioxygenase 1 (CDO1) is frequently methylated, and its
expression is decreased in many human cancers including breast cancer (BC). However …
expression is decreased in many human cancers including breast cancer (BC). However …
MDM4: What do we know about the association between its polymorphisms and cancer?
GM Almeida, AC Castilho, D Adamoski… - Medical Oncology, 2022 - Springer
MDM4 is an important p53-negative regulator, consequently, it is involved in cell
proliferation, DNA repair, and apoptosis regulation. MDM4 overexpression and amplification …
proliferation, DNA repair, and apoptosis regulation. MDM4 overexpression and amplification …
[HTML][HTML] Inhibiting DNA methyltransferase DNMT3B confers protection against ferroptosis in nucleus pulposus and ameliorates intervertebral disc degeneration via …
J Chen, X Yang, Q Li, J Ma, H Li, L Wang… - Free Radical Biology …, 2024 - Elsevier
Epigenetic changes are important considerations for degenerative diseases. DNA
methylation regulates crucial genes by epigenetic mechanism, impacting cell function and …
methylation regulates crucial genes by epigenetic mechanism, impacting cell function and …
Methylation status of LDLR, PCSK9 and LDLRAP1 is associated with cardiovascular events in familial hypercholesterolemia
E Silva Rodrigues Marçal, JB Borges, GM Bastos… - …, 2024 - Taylor & Francis
Aim: Methylation of LDLR, PCSK9 and LDLRAP1 CpG sites was assessed in patients with
familial hypercholesterolemia (FH). Methods: DNA methylation of was analyzed by …
familial hypercholesterolemia (FH). Methods: DNA methylation of was analyzed by …
CMV/AAT promoter of MAR-based episomal vector enhanced transgene expression in human hepatic cells
J Zhang, TY Wang, C Zhang, C Mi, S Geng, Y Tang… - 3 Biotech, 2023 - Springer
We have previously developed a non-viral episomal vector based on matrix attachment
region (MAR) that can facilitate plasmid replication episomally in mammal cells. In this study …
region (MAR) that can facilitate plasmid replication episomally in mammal cells. In this study …
Genome-wide temporal landscaping of DNA methylation in pregnant women delivering at term: a GARBH-InI study
Background: We performed an epigenome-wide longitudinal DNA methylation study on an
Indian cohort of pregnant women, GARBH-Ini, at three time points during pregnancy and at …
Indian cohort of pregnant women, GARBH-Ini, at three time points during pregnancy and at …
[HTML][HTML] DNA Tandem Repeats as Iterable Objects to Count Cell Divisions: A Computational Model
MFG Regolini - Advances in Bioscience and Biotechnology, 2024 - scirp.org
Cell lineages of nematodes are completely known: the adult male of Caenorhabditis
elegans contains 1031 somatic cells, the hermaphrodite 959, not one more, not one less; …
elegans contains 1031 somatic cells, the hermaphrodite 959, not one more, not one less; …
[PDF][PDF] In silico primer design and CpG island detection in HSP90 gene chicken (Gallus gallus)
NS Ummah, A Aryani… - … : Jurnal Ilmiah Biologi, 2022 - journal3.uin-alauddin.ac.id
The HSP90 gene can be used as a marker of heat stress in chickens. The isoforms of the
chicken HSP90 gene are HSP90 alpha (HSP90AA1 and HP90AB1) and HSP90 beta …
chicken HSP90 gene are HSP90 alpha (HSP90AA1 and HP90AB1) and HSP90 beta …