[HTML][HTML] Biological potential and therapeutic effectiveness of pteryxin in medicine. A viable alternative to current remedies for the treatment of human disorders

K Patel, DK Patel - Pharmacological Research-Modern Chinese Medicine, 2024 - Elsevier
Abstract Background Herbal medicine, including Chinese herbal medicines is getting
attention in the scientific research due to their long historical applications and reliable …

[HTML][HTML] Proteomic alterations in the cerebellum and hippocampus in an Alzheimer's disease mouse model: alleviating effect of palmatine

I Kiris, W Kukula-Koch, M Karayel-Basar, B Gurel… - Biomedicine & …, 2023 - Elsevier
Alzheimer's disease (AD) is one of the most prevalent diseases that lead to memory
deficiencies, severe behavioral abnormalities, and ultimately death. The need for more …

[HTML][HTML] Naturally Inspired Coumarin Derivatives in Alzheimer's Disease Drug Discovery: Latest Advances and Current Challenges

R Orioli, F Belluti, S Gobbi, A Rampa, A Bisi - Molecules, 2024 - ncbi.nlm.nih.gov
The main feature of neurodegenerative diseases, including Alzheimer's disease, is the
network of complex and not fully recognized neuronal pathways and targets involved in their …

Detection of early proteomic alterations in 5xFAD Alzheimer's disease neonatal mouse model via MALDI‐MSI

I Uras, M Karayel‐Basar, B Sahin… - Alzheimer's & …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder, characterized by
memory deficit and dementia. AD is considered a multifactorial disorder where multiple …

Scopoletin inhibits PDGF-BB-induced proliferation and migration of airway smooth muscle cells by regulating NF-κB signaling pathway

Z Fan, D Tang, Q Wu, Q Huang, J Song… - Allergologia et …, 2022 - all-imm.com
Background: Asthma is a common chronic inflammatory disease of the airway, and airway
remodeling and the proliferation mechanism of airway smooth muscle cells (ASMCs) is of …

A Coumarin− Donepezil Hybrid as a Blood− Brain Barrier Permeable Dual Cholinesterase Inhibitor: Isolation, Synthetic Modifications, and Biological Evaluation of …

A Sharma, VK Nuthakki, S Gairola, B Singh… - …, 2022 - Wiley Online Library
Plants have immensely contributed to the drug discovery for neurodegenerative diseases.
Herein, we undertook the phytochemical investigation of Nardostachys jatamansi (D. Don) …

Detection of proteomic alterations at different stages in a Huntington's disease mouse model via matrix‐assisted laser desorption/ionization mass spectrometry (MALDI …

M Karayel‐Basar, I Uras, I Kiris… - European Journal of …, 2023 - Wiley Online Library
Huntington's disease (HD) is a progressive and irreversible neurodegenerative disease
leading to the inability to carry out daily activities and for which no cure exists. The …

[PDF][PDF] 5× FAD 转基因小鼠在阿尔茨海默病研究中的应用进展

刘怡端, 刘翼骁, 韩欣园, 肖依彤… - 中国实验动物学报, 2024 - zgbjyx.cnjournals.com
Transgenic 5× FAD mice are APP/PS1 transgenic mice carrying five familial Alzheimer's
disease (AD) gene mutations. Beta-amyloid precursor protein (amyloid precursor protein …

O-demethyl galantamine alters protein expression in cerebellum of 5xFAD mice

İ Kiriş, M KARAYEL BAŞAR, B Gurel… - Turkish Journal of …, 2024 - journals.tubitak.gov.tr
Background/aim: Alzheimer's disease (AD), one of the most common health issues, is
characterized by memory loss, severe behavioral disorders, and eventually death. Despite …