Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Diabetes mellitus is a heterogeneous chronic metabolic disorder characterized by the
presence of hyperglycemia, commonly preceded by a prediabetic state. The excess of blood …

Obesity has been associated with oxidative stress. Obese patients are at increased risk for
diabetic cognitive dysfunction, indicating a pathological link between obesity, oxidative …

Type 2 diabetes mellitus (T2DM) patients are at a higher risk of developing Alzheimer's
disease (AD). Mounting evidence suggests the emerging important role of circadian rhythms …

Melatonin interacts in multiple ways with microglia, both directly and, via routes of crosstalk
with astrocytes and neurons, indirectly. These effects of melatonin are of relevance in terms …

The circadian clock acts a pivotal part in human daily physiology and metabolism. Excess
alcohol consumption disturbs the circadian rhythm of several metabolism-related genes of …

Ferroptosis, a novel type of cell death mediated by the iron‐dependent lipid peroxidation,
contributes to the pathogenesis of the intervertebral disc degeneration (IDD). Increasing …

The aim of this review is to explore the relationship between melatonin, free radicals, and
non-excitatory amino acids, and their role in stroke and aging. Melatonin has garnered …

Acrylamide is a toxic compound that is produced widely during food processing, but whether
the daily dietary consumption of acrylamide can impair the cognitive dysfunction in diabetic …

Sphingosine receptors (S1PRs) are implicated in the progression of neurodegenerative
diseases and metabolic disorders like obesity and type 2 diabetes (T2D). The link between …