The primary structure of G proteins as deduced from purified proteins and cloned subunits is
presented. When known, their functions are discussed, as are recent data on direct …

Hormones, neurotransmitters, and autacoids interact with specific receptors and thereby
trigger a series of molecular events that ultimately produce their biological effects. These …

Specific antisera were produced to peptides representing the carboxyl termini of three
subtypes of phosphatidylinositol-specific phospholipase C (PIPLC) beta which have been …

We have examined the ligand regulation and G protein selectivity of the human cannabinoid
CB1 and CB2 receptors by an in situ reconstitution technique directly measuring G protein …

Mastoparan (MP), a cationic, amphiphilic tetradecapeptide, stimulates guanine nucleotide
exchange by GTP-binding regulatory proteins (G proteins) in a manner similar to that of G …

EPIDERMAL growth factor, and its human homologue urogastrone (EGF/URO) 1, are
secreted by the gut-associated salivary and Brunner's glands2, 3. Recombinant EGF/URO is …

A complementary DNA that encodes a bovine brain, calmodulin-sensitive (type I)
adenylylcyclase has been inserted into the baculovirus genome under the control of the …

Cloning of a complementary DNA (cDNA) for Gz alpha, a newly appreciated member of the
family of guanine nucleotide-binding regulatory proteins (G proteins), has allowed …

The subfamily of guanine nucleotide-binding regulatory (G proteins) designated Gq has
been shown to regulate the activity of phospholipase C by reconstitution. However, the role …

Myristoylated recombinant proteins can be synthesized in Escherichia coli by concurrent
expression of the enzyme myristoyl-CoA: protein N-myristoyl-transferase with its protein …