The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Osmotic stress signaling and osmoadaptation in yeasts

S Hohmann - Microbiology and molecular biology reviews, 2002 - Am Soc Microbiol
The ability to adapt to altered availability of free water is a fundamental property of living
cells. The principles underlying osmoadaptation are well conserved. The yeast …

Candidalysin is a fungal peptide toxin critical for mucosal infection

DL Moyes, D Wilson, JP Richardson, S Mogavero… - Nature, 2016 - nature.com
Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial
pathogens which disrupt epithelial barrier function, damage cells and activate or modulate …

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen

IV Ene, AK Adya, S Wehmeier, AC Brand… - Cellular …, 2012 - Wiley Online Library
The survival of all microbes depends upon their ability to respond to environmental
challenges. To establish infection, pathogens such as C andida albicans must mount …

Role of the Hog1 Stress-activated Protein Kinase in the Global Transcriptional Response to Stress in the Fungal Pathogen Candida albicans

B Enjalbert, DA Smith, MJ Cornell, I Alam… - Molecular biology of …, 2006 - Am Soc Cell Biol
The resistance of Candida albicans to many stresses is dependent on the stress-activated
protein kinase (SAPK) Hog1. Hence we have explored the role of Hog1 in the regulation of …

Stress adaptation in a pathogenic fungus

AJP Brown, S Budge, D Kaloriti… - Journal of …, 2014 - journals.biologists.com
Candida albicans is a major fungal pathogen of humans. This yeast is carried by many
individuals as a harmless commensal, but when immune defences are perturbed it causes …

MAP kinases in fungal pathogens

JR Xu - Fungal Genetics and Biology, 2000 - Elsevier
MAP kinases in eukaryotic cells are well known for transducing a variety of extracellular
signals to regulate cell growth and differentiation. Recently, MAP kinases homologous to the …

Role of the Mitogen-Activated Protein Kinase Hog1p in Morphogenesis and Virulence of Candida albicans

R Alonso-Monge, F Navarro-Garcia… - Journal of …, 1999 - Am Soc Microbiol
The relevance of the mitogen-activated protein (MAP) kinase Hog1p in Candida albicans
was addressed through the characterization of C. albicans strains without a functional HOG1 …

The Hog1 Mitogen-Activated Protein Kinase Is Essential in the Oxidative Stress Response and Chlamydospore Formation in Candidaalbicans

R Alonso-Monge, F Navarro-García, E Román… - Eukaryotic …, 2003 - Am Soc Microbiol
Candida albicans mutants with mutations in mitogen-activated protein (MAP) kinase HOG1
displayed an increased sensitivity to agents producing reactive oxygen species, such as …

The MAP kinase signal transduction network in Candida albicans

RA Monge, E Roman, C Nombela, J Pla - Microbiology, 2006 - microbiologyresearch.org
MAP (mitogen-activated protein) kinase-mediated pathways are key elements in sensing
and transmitting the response of cells to environmental conditions by the sequential action of …