Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …

Doxorubicin (DOX) is a chemotherapeutic agent with marked, dose-dependent cardiotoxicity
that leads to tachycardia, atrial and ventricular arrhythmia, and irreversible heart failure …

Preeclampsia is a common pregnancy complication, affecting 2% to 8% of pregnancies
worldwide, and is an important cause of both maternal and fetal morbidity and mortality …

Abstract Significance: Hydrogen sulfide (H2S) metabolism leads to the formation of oxidized
sulfide species, including polysulfide, persulfide, and others. Evidence is emerging that …

Although the cause of preeclampsia, a pregnancy complication with significant maternal and
neonatal morbidity, has not been fully characterized, placental ischemia attributable to …

Preeclampsia affects∼ 2–8% of pregnancies worldwide. It is associated with increased long-
term maternal cardiovascular disease risk. This study assesses the effect of the …

Abstract Hydrogen sulfide (H 2 S), a gaseous signalling molecule, is important in numerous
physiological and pathophysiological processes. Despite its initial identification as an …

Background: In preeclampsia, a hypertensive disorder of pregnancy, the poor remodeling of
spiral arteries leads to placental hypoperfusion and ischemia, provoking generalized …

Significance: The endogenous hydrogen sulfide (H2S) pathway produces an array of
biological effects that vary depending on the bodily region. In addition, the H2S pathway's …