Exposure of biological cells to high-voltage, short-duration electric pulses causes a transient
increase in their plasma membrane permeability, allowing transmembrane transport of …

Molecular dynamics (MD) simulation is a useful technique to study the interaction between
molecules and how they are affected by various processes and processing conditions. This …

In the recent years, the possibility of utilizing extracellular vesicles for drug delivery purposes
has been investigated in various models, suggesting that these vesicles may have such …

Carbohydrates play an essential role in a large number of chemical and biochemical
processes. High structural diversity and conformational heterogeneity make it problematic to …

Simple sugars such as glucose and sucrose are ubiquitous in all organisms. One
remarkable property of these small solutes is their ability to protect biomembranes against …

Sugars function as bioprotectants by stabilizing biomolecules during dehydration, thermal
stress, and freeze–thaw cycles. A buildup of sugars occurs in many organisms upon their …

It is well-known that sugars protect membrane structures against fusion and leakage. Here,
we have investigated the interaction between different sugars (sucrose, trehalose, and …

All-atom molecular dynamics simulations have been used to investigate the adsorption of
low molecular weight hyaluronic acid to lipid membranes. We have determined the …

Disaccharides are well-known for their membrane protective ability. Interaction between
sugars and multicomponent membranes, however, remains largely unexplored. Here, we …

Cells can expand their plasma membrane laterally by unfolding membrane undulations and
by exocytosis. Here, we describe a third mechanism involving invaginations held shut by the …