Recent advances in zinc oxide nanoparticles (ZnO NPs) for cancer diagnosis, target drug delivery, and treatment
Simple Summary Despite breakthroughs in medicine, cancer remains one of the most feared
diseases. Traditionally, chemotherapies have been the treatment of choice. However …
diseases. Traditionally, chemotherapies have been the treatment of choice. However …
GDF‐15 as a target and biomarker for diabetes and cardiovascular diseases: a translational prospective
R Adela, SK Banerjee - Journal of diabetes research, 2015 - Wiley Online Library
Growth differentiation factor‐15 (GDF‐15) is a stress responsive cytokine. It is highly
expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells, and vascular …
expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells, and vascular …
Paradoxical roles of antioxidant enzymes: basic mechanisms and health implications
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated from
aerobic metabolism, as a result of accidental electron leakage as well as regulated …
aerobic metabolism, as a result of accidental electron leakage as well as regulated …
Oxidative stress, inflammation, and cancer: how are they linked?
S Reuter, SC Gupta, MM Chaturvedi… - Free radical biology and …, 2010 - Elsevier
Extensive research during the past 2 decades has revealed the mechanism by which
continued oxidative stress can lead to chronic inflammation, which in turn could mediate …
continued oxidative stress can lead to chronic inflammation, which in turn could mediate …
Oxidative stress and pathophysiology of ischemic stroke: novel therapeutic opportunities
R Rodrigo, R Fernandez-Gajardo… - CNS & Neurological …, 2013 - ingentaconnect.com
Stroke is the second leading cause of death, after ischemic heart disease, and accounts for
9% of deaths worldwide. According to the World Health Organization [WHO], 15 million …
9% of deaths worldwide. According to the World Health Organization [WHO], 15 million …
Oxytosis/ferroptosis—(Re-) emerging roles for oxidative stress-dependent non-apoptotic cell death in diseases of the central nervous system
Although nerve cell death is the hallmark of many neurological diseases, the processes
underlying this death are still poorly defined. However, there is a general consensus that …
underlying this death are still poorly defined. However, there is a general consensus that …
Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy
K Strebhardt - Nature reviews Drug discovery, 2010 - nature.com
The polo-like kinase 1 (PLK1) acts in concert with cyclin-dependent kinase 1–cyclin B1 and
Aurora kinases to orchestrate a wide range of critical cell cycle events. Because PLK1 has …
Aurora kinases to orchestrate a wide range of critical cell cycle events. Because PLK1 has …
Cancer chemoprevention mechanisms mediated through the Keap1–Nrf2 pathway
The cap'n'collar (CNC) bZIP transcription factor Nrf2 controls expression of genes for
antioxidant enzymes, metal-binding proteins, drug-metabolising enzymes, drug transporters …
antioxidant enzymes, metal-binding proteins, drug-metabolising enzymes, drug transporters …
Oxidative stress and hormesis in evolutionary ecology and physiology
D Costantini - A marriage between mechanistic and evolutionary …, 2014 - Springer
Research programmes on oxidative stress and hormesis are wide ranging. Biomedical and
toxicological sciences have traditionally centralised such research, but in the last years we …
toxicological sciences have traditionally centralised such research, but in the last years we …
Is the oxidative stress theory of aging dead?
VI Pérez, A Bokov, H Van Remmen, J Mele… - … et Biophysica Acta (BBA …, 2009 - Elsevier
Currently, the oxidative stress (or free radical) theory of aging is the most popular
explanation of how aging occurs at the molecular level. While data from studies in …
explanation of how aging occurs at the molecular level. While data from studies in …