In this review, the most relevant data regarding serotonin (5-hydroxytryptamine, 5-
HT)/dopamine (DA) interaction in the brain, as studied by both in vivo and in vitro …

It is well-documented that serotonin (5-HT) exerts its pharmacological effects through a
series of 5-HT receptors. The most recently identified member of this family, 5-HT7, was first …

Alcohol and drug abuse take a large toll on society and affected individuals. However, very
few effective treatments are currently available to treat alcohol and drug addiction. Basic and …

Serotonergic neurotransmission is mediated by at least 14 subtypes of 5-HT receptors.
Among these, the CNS serotonin receptor 7 (5-HTR7) is involved in diverse physiological …

The aim of the present study was to examine the effect of the selective 5-HT7 receptor
antagonist (2R)-1-[(3-hydroxyphenyl) sulfonyl]-2-[2-(4-methyl-1-piperidinyl) ethyl] pyrrolidine …

Methylphenidate (MPH) administration to adolescent rodents produces persistent region‐
specific changes in brain reward circuits and alterations of reward‐based behavior. We …

HT 7 receptors have been linked to a number of psychiatric disorders including anxiety and
depression. The localization of 5-HT 7 receptors in the thalamus, a key sensory processing …

Serotonin (5-HT) exerts its diverse physiological and pharmacological effects through the
activation of multiple receptor subtypes. One of the newest members of this family is the 5 …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive
degeneration of monoaminergic central pathways such as the serotonergic. The …

Lurasidone is a novel benzisothiazole antipsychotic drug for the treatment of schizophrenia.
Of the antipsychotic drugs, lurasidone has the highest affinity for the 5-hydroxytryptamine (5 …