Skeletal muscle fat infiltration (known as myosteatosis) is an ectopic fat depot that increases
with aging and is recognized to negatively correlate with muscle mass, strength, and mobility …

In a world in which life expectancy is increasing, understanding and promoting healthy
aging becomes a contemporary demand. In the elderly, a sterile, chronic and low-grade …

Background Calf circumference (CC) is used in geriatric studies as a simple and practical
skeletal muscle (SM) marker for diagnosing low SM and sarcopenia. Currently applied CC …

Obesity is associated with functional limitations in muscle performance and increased
likelihood of developing a functional disability such as mobility, strength, postural and …

Muscle's structural composition is an important factor underlying muscle strength and
physical function in older adults. There is an increasing amount of research to support the …

A growing body of scientific literature suggests that not only changes in skeletal muscle
mass, but also other factors underpinning muscle quality, play a role in the decline in …

In 2005, it was estimated that more than 20 million people in the United States had diabetes.
Approximately 30% of these people had undiagnosed cases. Increased risk for diabetes is …

Obesity can cause a decline in contractile function of skeletal muscle, thereby reducing
mobility and promoting obesity-associated health risks. We reviewed the literature to …

Physical therapists commonly treat people with diabetes for a wide variety of diabetes-
associated impairments, including those from diabetes-related vascular disease. Diabetes is …

Key points Muscle infiltration with adipose tissue (IMAT) is common and associated with loss
of skeletal muscle strength and physical function across a diverse set of pathologies …