The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy
not only seriously reduces people's quality of life and increases morbidity and mortality, but …

Cardiovascular disease (CVD) is one of the leading causes of death and disability, and has
always been a hotspot in clinical and scientific research. The illness brings a heavy …

Parkinson's disease (PD) is the second most common progressive age-related
neurodegenerative disorder. Paramount evidence shed light on the role of PI3K/AKT …

Exercise is a major beneficial contributor to muscle metabolism, and health benefits
acquired by exercise are a result of molecular shifts occurring across multiple molecular …

Aims Streptozotocin (STZ)-induced diabetic animal models have been widely used to study
diabetic myopathy; however, non-specific cytotoxic effects of high-dose STZ have been …

We have previously shown that phosphodiesterase 4 (PDE4) inhibition protects against
neuronal injury in rats following middle cerebral artery occlusion/reperfusion (MCAO/R) …

骨骼肌是胰岛素刺激下葡萄糖摄取的核心代谢组织, 负责人体高达85% 的葡萄糖代谢,
同时又是胰岛素抵抗的主要部位. 当机体长期处于高血糖时, 肌肉会受到一定程度的损害 …

Objective Exercise is a major regulator of muscle metabolism, and health benefits acquired
by exercise are a result of molecular shifts occurring across multiple OMIC levels (ie …

I declare that the work contained within this document was carried out in accordance with
the regulations of the Queen's University Belfast and complies with the criteria required by …