A comprehensive account on recent progress in pharmacological activities of benzimidazole derivatives

SR Brishty, MJ Hossain, MU Khandaker… - Frontiers in …, 2021 - frontiersin.org
Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest
among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole …

Two decades of recent advances of Ugi reactions: synthetic and pharmaceutical applications

MA Fouad, H Abdel-Hamid, MS Ayoup - RSC advances, 2020 - pubs.rsc.org
Multicomponent reactions (MCRs) are powerful synthetic tools in which more than two
starting materials couple with each other to form multi-functionalized compounds in a one …

Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review

WY Fang, L Ravindar, KP Rakesh… - European Journal of …, 2019 - Elsevier
At present more than 250 FDA approved chlorine containing drugs were available in the
market and many pharmaceutically important drug candidates in pre-clinical trials. Thus, it is …

Hydrazide–hydrazones as potential antimicrobial agents: overview of the literature since 2010

Ł Popiołek - Medicinal Chemistry Research, 2017 - Springer
Hydrazide–hydrazone derivatives are present in many bioactive molecules and display a
wide variety of biological activities, such as antibacterial, antitubercular, antifungal …

Therapeutic evolution of benzimidazole derivatives in the last quinquennial period

W Akhtar, MF Khan, G Verma… - European journal of …, 2017 - Elsevier
Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …

Electrochemically enabled chemoselective sulfonylation and hydrazination of indoles

YZ Zhang, ZY Mo, HS Wang, XA Wen, HT Tang… - Green …, 2019 - pubs.rsc.org
Environmentally benign electrochemically enabled chemoselective sulfonylation and
hydrazination of C2, C3-unsubstituted indoles with arylsulfonyl hydrazide in the presence of …

Promising antifungal agents: A minireview

KVSM Chandrika, S Sharma - Bioorganic & medicinal chemistry, 2020 - Elsevier
In the recent past, prevalence of life threatening fungal diseases have increased rapidly in
immune-compromised cases such as acquired immunodeficiency syndrome (AIDS), cancer …

Recent achievements in the synthesis of benzimidazole derivatives

NT Chung, VC Dung, DX Duc - RSC advances, 2023 - pubs.rsc.org
Benzimidazoles are a class of heterocyclic compounds in which a benzene ring is fused to
the 4 and 5 positions of an imidazole ring. Benzimidazole refers to the parent compound …

3D-QSAR study, docking molecular and simulation dynamic on series of benzimidazole derivatives as anti-cancer agents

L El Mchichi, K Tabti, R Kasmi, R El-Mernissi… - Journal of the Indian …, 2022 - Elsevier
Benzimidazole is an important heterocyclic organic compound which has a structural
analogy to nucleotides found in human body and hence is an important pharmacophore in …

Synthesis and antifungal potential of some novel benzimidazole-1, 3, 4-oxadiazole compounds

AÇ Karaburun, B Kaya Çavuşoğlu, U Acar Çevik… - Molecules, 2019 - mdpi.com
Discovery of novel anticandidal agents with clarified mechanisms of action, could be a
rationalist approach against diverse pathogenic fungal strains due to the rise of resistance to …