Neuroinflammation in cerebral ischemia and ischemia/reperfusion injuries: from pathophysiology to therapeutic strategies
A Jurcau, A Simion - International journal of molecular sciences, 2021 - mdpi.com
Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …
Despite significant advances in recanalization strategies, patients are still at risk for …
The dialogue between neuroinflammation and adult neurogenesis: mechanisms involved and alterations in neurological diseases
Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …
Role of interleukin-6 in cancer progression and therapeutic resistance
In the last several decades, the number of people dying from cancer-related deaths has not
reduced significantly despite phenomenal advances in the technologies related to diagnosis …
reduced significantly despite phenomenal advances in the technologies related to diagnosis …
[HTML][HTML] Role of IL-6 in the regulation of neuronal development, survival and function
The pleiotropic cytokine interleukin-6 (IL-6) is emerging as a molecule with both beneficial
and destructive potentials. It can exert opposing actions triggering either neuron survival …
and destructive potentials. It can exert opposing actions triggering either neuron survival …
[HTML][HTML] The pro-and anti-inflammatory properties of the cytokine interleukin-6
J Scheller, A Chalaris, D Schmidt-Arras… - Biochimica et Biophysica …, 2011 - Elsevier
Interleukin-6 is a cytokine not only involved in inflammation and infection responses but also
in the regulation of metabolic, regenerative, and neural processes. In classic signaling …
in the regulation of metabolic, regenerative, and neural processes. In classic signaling …
The role of markers of inflammation in traumatic brain injury
T Woodcock, MC Morganti-Kossmann - Frontiers in neurology, 2013 - frontiersin.org
Within minutes of a traumatic impact, a robust inflammatory response is elicited in the injured
brain. The complexity of this post-traumatic squeal involves a cellular component …
brain. The complexity of this post-traumatic squeal involves a cellular component …
Microglia enhance neurogenesis and oligodendrogenesis in the early postnatal subventricular zone
Y Shigemoto-Mogami, K Hoshikawa… - Journal of …, 2014 - Soc Neuroscience
Although microglia have long been considered as brain resident immune cells, increasing
evidence suggests that they also have physiological roles in the development of the normal …
evidence suggests that they also have physiological roles in the development of the normal …
Neuroinflammation and neurogenesis in Alzheimer's disease and potential therapeutic approaches
PS Sung, PY Lin, CH Liu, HC Su, KJ Tsai - International journal of …, 2020 - mdpi.com
In adult brain, new neurons are generated throughout adulthood in the subventricular zone
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …
The role of inflammatory cytokines as key modulators of neurogenesis
Neurogenesis is an important process in the regulation of brain function and behaviour,
highly active in early development and continuing throughout life. Recent studies have …
highly active in early development and continuing throughout life. Recent studies have …
Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia
Upregulation of the immune response may be involved in the pathogenesis of schizophrenia
with changes occurring in both peripheral blood and brain tissue. To date, microarray …
with changes occurring in both peripheral blood and brain tissue. To date, microarray …