Arterial smooth muscle cells (ASMCs), the predominant cell type within the arterial wall,
detect and respond to external mechanical forces. These forces can be derived from blood …

Cardiovascular tissue engineering (CVTE) aims to create living tissues, with the ability to
grow and remodel, as replacements for diseased blood vessels and heart valves. Despite …

Blood vessels grow and remodel in response to mechanical stimuli. Many computational
models capture this process phenomenologically, by assuming stress homeostasis, but this …

Cardiac morphogenesis relies on intricate intercellular signaling. Altered signaling impacts
cardiac function and is detrimental to embryonic survival. Here we report an unexpected …

Extracellular matrix (ECM) proteins in the mammary gland provide structure and regulate its
development and homeostasis. Alterations in its structure can regulate and support …

The Notch signaling pathway is one of the essential mediators of cell-cell communication
during development of multicellular organisms. Notch signaling is based on receptors and …