The C/EBP homologous protein (CHOP) transcription factor functions in endoplasmic reticulum stress-induced apoptosis and microbial infection
H Hu, M Tian, C Ding, S Yu - Frontiers in immunology, 2019 - frontiersin.org
Apoptosis is a form of cell death by which the body maintains the homeostasis of the internal
environment. Apoptosis is an initiative cell death process that is controlled by genes and is …
environment. Apoptosis is an initiative cell death process that is controlled by genes and is …
Effect of reactive oxygen species on the endoplasmic reticulum and mitochondria during intracellular pathogen infection of mammalian cells
J Lee, CH Song - Antioxidants, 2021 - mdpi.com
Oxidative stress, particularly reactive oxygen species (ROS), are important for innate
immunity against pathogens. ROS directly attack pathogens, regulate and amplify immune …
immunity against pathogens. ROS directly attack pathogens, regulate and amplify immune …
Role of apoptosis and autophagy in tuberculosis
A Lam, R Prabhu, CM Gross… - … of Physiology-Lung …, 2017 - journals.physiology.org
Tuberculosis (TB) is one of the oldest known human diseases and is transmitted by the
bacteria Mycobacterium tuberculosis (Mtb). TB has a rich history with evidence of TB …
bacteria Mycobacterium tuberculosis (Mtb). TB has a rich history with evidence of TB …
New findings of Toll-like receptors involved in Mycobacterium tuberculosis infection
M Faridgohar, H Nikoueinejad - Pathogens and global health, 2017 - Taylor & Francis
Tuberculosis (TB), an important issue in the present age, affects millions of people each
year. The infectious agent of TB, Mycobacterium tuberculosis (Mtb), interacts with the …
year. The infectious agent of TB, Mycobacterium tuberculosis (Mtb), interacts with the …
BAG2 ameliorates endoplasmic reticulum stress-induced cell apoptosis in Mycobacterium tuberculosis-infected macrophages through selective autophagy
S Liang, F Wang, C Bao, J Han, Y Guo, F Liu, Y Zhang - Autophagy, 2020 - Taylor & Francis
ABSTRACT BAG2 (BCL2 associated athanogene 2) is associated with cell fate
determination in response to various pathological conditions. However, the effects of BAG2 …
determination in response to various pathological conditions. However, the effects of BAG2 …
Regnase-1, a rapid response ribonuclease regulating inflammation and stress responses
RNA-binding proteins (RBPs) are central players in post-transcriptional regulation and
immune homeostasis. The ribonuclease and RBP Regnase-1 exerts critical roles in both …
immune homeostasis. The ribonuclease and RBP Regnase-1 exerts critical roles in both …
[HTML][HTML] Host-mycobacteria conflict: Immune responses of the host vs. the mycobacteria TLR2 and TLR4 ligands and concomitant host-directed therapy
KP Pattanaik, S Sengupta, BP Jit, R Kotak… - Microbiological …, 2022 - Elsevier
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is one of the most grievous
infectious diseases with long-term morbidity and unpredicted mortality rates globally. Thus …
infectious diseases with long-term morbidity and unpredicted mortality rates globally. Thus …
Mycobacterium bovis Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line
Y Cui, D Zhao, S Sreevatsan, C Liu, W Yang… - Frontiers in cellular …, 2016 - frontiersin.org
Mycobacterium bovis (M. bovis) is highly adapted to macrophages and has developed
multiple mechanisms to resist intracellular assaults. However, the host cells in turn deploy a …
multiple mechanisms to resist intracellular assaults. However, the host cells in turn deploy a …
Recombinant Treponema pallidum protein Tp0768 promotes proinflammatory cytokine secretion of macrophages through ER stress and ROS/NF-κB pathway
W Li, X Zhou, J Cai, F Zhao, T Cao, L Ning… - Applied Microbiology …, 2021 - Springer
In response to danger signals, macrophages rapidly produce many inflammatory cytokines
that trigger the cascade release of inflammatory mediators, leading to tissue damage, which …
that trigger the cascade release of inflammatory mediators, leading to tissue damage, which …
Impaired mitophagy induces antimicrobial responses in macrophages infected with Mycobacterium tuberculosis
J Lee, SA Lee, SH Son, JA Choi, TD Nguyen, J Kim… - Cell & Bioscience, 2023 - Springer
Background Mitophagy, mitochondrial selective autophagy, plays a pivotal role in the
maintenance of cellular homeostasis in response to cellular stress. However, the role of …
maintenance of cellular homeostasis in response to cellular stress. However, the role of …