Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …

Biofilms are communities of microbial cells that underpin diverse processes including
sewage bioremediation, plant growth promotion, chronic infections and industrial biofouling …

Microbes or danger signals trigger inflammasome sensors, which induce polymerization of
the adaptor ASC and the assembly of ASC specks. ASC specks recruit and activate caspase …

Many natural biological systems—such as biofilms, shells and skeletal tissues—are able to
assemble multifunctional and environmentally responsive multiscale assemblies of living …

Current interest in amyloid fibrils stems from their involvement in neurodegenerative and
other diseases and from their role as an alternative structural state for many peptides and …

Amyloid is a distinct β-sheet-rich fold that many proteins can acquire. Frequently associated
with neurodegenerative diseases in humans, including Alzheimer's, Parkinson's and …

Fibrillar protein aggregates are a hallmark of a range of human disorders, from prion
diseases to dementias, but are also encountered in several functional contexts. Yet, the …

Many bacteria assemble extracellular amyloid fibers on their cell surface. Secretion of
proteins across membranes and the assembly of complex macromolecular structures must …

Microbial protein nanowires are emerging as an alternative to abiotic nanowires for
electronics applications. Microbial nanowires are sustainably produced, robust, non-toxic …

Biofilms of enteric bacteria are highly complex, with multiple components that interact to
fortify the biofilm matrix. Within biofilms of enteric bacteria such as Escherichia coli and …