Biological activity requires a solvent that can provide a suitable environment, which satisfies
the twin need for stability and the ability to change. Among all the solvents water plays the …

When described by a one-dimensional reaction coordinate, pair-reaction rates in a solvent
depend, in addition to the potential barrier height and the friction coefficient, on the potential …

Liquid-liquid phase separation (LLPS) can drive a multitude of cellular processes by
compartmentalizing biological cells via the formation of dense liquid biomolecular …

Water is essential for the structure, dynamics, energetics, and thus the function of
biomolecules. It is a formidable challenge to elicit, in microscopic detail, the role of the …

The viscosity of aqueous electrolyte solutions exhibits well-known composition-dependent
anomalies that show certain definitive trends and universal features. The viscosity of LiCl …

Liquid–liquid phase separation (LLPS) plays a key role in the compartmentalization of cells
via the formation of biomolecular condensates. Here, we combined atomistic molecular …

We have studied in silico the effect of proline, a model cosolvent, on local and global friction
coefficients in (un) folding of several typical alanine-based α-helical peptides. Local friction …

Protein dynamics is strongly influenced by the surrounding environment and physiological
conditions. Here we employ broadband megahertz-to-terahertz spectroscopy to explore the …

The coupling between the conformational fluctuations of DNA and its surrounding
environment, consisting of water and ions in solution, remains poorly understood and …

Despite its rigid structure, DNA is a remarkably flexible molecule. Flexibility is essential for
biological functions (such as transcription and gene repair), which require large-amplitude …