Stroke is the cause of about 10% of all epilepsy and 55% of newly diagnosed seizures
among the elderly. Although recent advances in acute stroke therapy have improved …

Stroke is among the most common causes of epilepsy after middle age. Patients with
poststroke epilepsy (PSE) differ in several respects from patients with other forms of …

Objective Epilepsy is a common neurological disorder that affects 1% of the population.
Approximately, 30% of individuals with epilepsy are refractory to treatment, highlighting the …

Nowadays a substantial armamentarium of antiepileptic drugs (AEDs) is available, including
drugs with different mechanisms of action, pharmacokinetics, efficacy and tolerability; …

Statins, cholesterol lowering drugs, have been demonstrated to exert beneficial effects in
other conditions such as primary and progressing neurodegenerative diseases beyond their …

Starting with cholesterol homeostasis, the first part of the review addresses various aspects
of cholesterol metabolism in neuronal and glial cells and the mutual crosstalk between the …

Sodium valproate (VPA), an antiepileptic drug, may cause dose‐and time‐dependent
hepatotoxicity. However, its iatrogenic molecular mechanism and the rescue therapy are …

Stroke is a huge burden on our society and this is expected to grow in the future due to the
aging population and the associated co-morbidities. The improvement of acute stroke care …

Currently available antiepileptic drugs (AEDs) fail to control seizures in 30% of patients.
Genomics-based drug repurposing (GBR) offers the potential of savings in the time and cost …

The usage of dietary supplements and other natural products to treat neurological diseases
has been growing over time, and accumulating evidence suggests that flavonoids possess …