Adenosine is an endogenous nucleoside with a short half-life that regulates many
physiological functions involving the heart and cardiovascular system. Among the …

The contribution of natural products (NPs) to cardiovascular medicine has been extensively
documented, and many have been used for centuries. Cardiovascular disease (CVD) is the …

Myocardial infarction, commonly known as heart attack, evolves from the rupture of unstable
atherosclerotic plaques to coronary thrombosis and myocardial ischemia–reperfusion injury …

Abstract The coronavirus disease (COVID-19), caused by SARS-CoV-2 infection, accounts
for more than 2.4 million deaths worldwide, making it the main public health problem in …

Current studies have shown that gut microbiota may be closely related to the severity of
coronavirus disease 2019 (COVID-19) by regulating the host immune response. Qing-Fei …

Platelet activation plays a key role in cardiovascular diseases. The generation of
mitochondrial reactive oxygen species (ROS) has been described as a critical step required …

Traditionally, platelets are known to play an important role in haemostasis and thrombosis;
however, they serve also as important modulators of inflammation and immunity. Platelets …

For over a year, the coronavirus disease 2019 has been affecting the world population by
causing severe tissue injuries and death in infected people. Adenosine triphosphate (ATP) …

Thrombotic events are common causes of morbidity and mortality in the elderly. Age-
accelerated vascular injury is commonly considered to result from increased oxidative …

Purinergic signaling, mediated mainly by G protein-coupled P2Y receptors (P2YRs), is now
attracting attention as a new therapeutic target for preventing or treating cardiovascular …