[HTML][HTML] The fast-growing business of Serine ADP-ribosylation

EJ Longarini, I Matic - Dna Repair, 2022 - Elsevier
ADP-ribosylation (ADPr) is a widespread post-translational modification (PTM) which
encompasses all kingdoms of life. It is employed by bacteria and viruses in their war against …

Poly‐ADP‐ribosylation dynamics, signaling, and analysis

RQ Al‐Rahahleh, RW Sobol - Environmental and Molecular …, 2024 - Wiley Online Library
ADP‐ribosylation is a reversible post‐translational modification that plays a role as a
signaling mechanism in various cellular processes. This modification is characterized by its …

Live cell detection of poly (ADP-ribose) for use in genetic and genotoxic compound screens

CA Koczor, AJ Haider, KM Saville, J Li, JF Andrews… - Cancers, 2022 - mdpi.com
Simple Summary Poly (ADP-ribose)(PAR) functions in genome repair, cell metabolism, and
cancer treatment; however, in vivo molecular tools to assess PAR levels are not readily …

Development and characterization of new tools for detecting poly (ADP-ribose) in vitro and in vivo

S Challa, KW Ryu, AL Whitaker, JC Abshier… - Elife, 2022 - elifesciences.org
ADP-ribosylation (ADPRylation) is a reversible post-translation modification resulting in the
covalent attachment of ADP-ribose (ADPR) moieties on substrate proteins. Naturally …

A Genetically Encoded Sensor for Real-Time Monitoring of Poly-ADP-Ribosylation Dynamics In Vitro and in Cells

A Thomas, K Upadhyaya, D Bejan, H Adoff… - ACS …, 2024 - ACS Publications
ADP-ribosylation, the transfer of ADP-ribose (ADPr) from nicotinamide adenine dinucleotide
(NAD+) groups to proteins, is a conserved post-translational modification (PTM) that occurs …

Detecting Poly (ADP-Ribose) In Vitro and in Cells Using PAR Trackers

S Challa, AL Whitaker, WL Kraus - Poly (ADP-Ribose) Polymerase …, 2022 - Springer
ADP-ribosylation (ADPRylation) is a reversible posttranslational modification resulting in the
covalent attachment of ADP-ribose (ADPR) moieties on substrate proteins. Naturally …

[HTML][HTML] Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage

RQ Al-Rahahleh, KM Saville, JF Andrews, Z Wu… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Protein poly-ADP-ribosylation (PARylation) is a post-translational modification formed by
transfer of successive units of ADP-ribose to target proteins to form poly-ADP-ribose (PAR) …

Rational Design of ssODN to Correct Mutations by Gene Editing

OV Volodina, AA Anuchina, MI Zainitdinova… - Biochemistry …, 2022 - Springer
Gene editing allows to make a variety of targeted changes in genome, which can potentially
be used to treat hereditary human diseases. Despite numerous studies in this area …

Development and Characterization of PAR-Trackers: New Tools for Detecting Poly (ADP-ribose) In Vitro and In Vivo

S Challa, KW Ryu, AL Whitaker, JC Abshier… - bioRxiv, 2021 - biorxiv.org
ADP-ribosylation (ADPRylation) is a reversible post-translation modification resulting in the
covalent attachment of ADP-ribose (ADPR) moieties on substrate proteins. Naturally …

Учредители: Российская академия наук

ОВ ВОЛОДИНА, АА АНУЧИНА, МИ ЗАЙНИТДИНОВА… - БИОХИМИЯ, 2022 - elibrary.ru
Геномное редактирование позволяет целенаправленно вносить разнообразные
изменения в геном, что потенциально может быть использовано для лечения …