Ileal bile acid transporter inhibition as an anticholestatic therapeutic target in biliary atresia and other cholestatic disorders
Biliary atresia is a rare cholestatic liver disease that presents in infants and rapidly advances
to death in the absence of intervention. As a result of blockage or destruction of the biliary …
to death in the absence of intervention. As a result of blockage or destruction of the biliary …
[PDF][PDF] Screening and outcomes in biliary atresia: summary of a National Institutes of Health workshop
RJ Sokol, RW Shepherd, R Superina, JA Bezerra… - …, 2007 - Wiley Online Library
Biliary atresia is the most common cause of end‐stage liver disease in the infant and is the
leading pediatric indication for liver transplantation in the United States. Earlier diagnosis (< …
leading pediatric indication for liver transplantation in the United States. Earlier diagnosis (< …
Impact of age at Kasai operation on its results in late childhood and adolescence: a rational basis for biliary atresia screening
MO Serinet, BE Wildhaber, P Broue, A Lachaux… - …, 2009 - publications.aap.org
BACKGROUND. Increased age at surgery has a negative impact on results of the Kasai
operation for biliary atresia in infancy and early childhood. It remained unclear if an age …
operation for biliary atresia in infancy and early childhood. It remained unclear if an age …
A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000
BL Shneider, MB Brown, B Haber, PF Whitington… - The Journal of …, 2006 - Elsevier
OBJECTIVE: To determine the prognostic factors and optimal approaches to the diagnosis
and management of biliary atresia, the leading indication for liver transplantation in children …
and management of biliary atresia, the leading indication for liver transplantation in children …
[PDF][PDF] Outcome in adulthood of biliary atresia: a study of 63 patients who survived for over 20 years with their native liver
P Lykavieris, C Chardot, M Sokhn, F Gauthier… - …, 2005 - Wiley Online Library
To define the long‐term prognosis of children undergoing the Kasai operation for biliary
atresia, a retrospective study was undertaken comprising 271 patients operated between …
atresia, a retrospective study was undertaken comprising 271 patients operated between …
Biliary atresia: clinical aspects
M Davenport - Seminars in pediatric surgery, 2012 - Elsevier
Biliary atresia (BA) remains an enigmatic disease with a degree of etiologic heterogeneity. A
number of variants can be defined clinically, and these include the syndromic group …
number of variants can be defined clinically, and these include the syndromic group …
The anatomic pattern of biliary atresia identified at time of Kasai hepatoportoenterostomy and early postoperative clearance of jaundice are significant predictors of …
R Superina, JC Magee, ML Brandt, PJ Healey… - Annals of …, 2011 - journals.lww.com
Objective: The goals of this study were to describe the clinical and anatomic features of
infants undergoing Kasai portoenterostomy (KPE) for biliary atresia (BA) and to examine …
infants undergoing Kasai portoenterostomy (KPE) for biliary atresia (BA) and to examine …
Incidence of biliary atresia and timing of hepatoportoenterostomy in the United States
PC Hopkins, N Yazigi, CM Nylund - The Journal of pediatrics, 2017 - Elsevier
Objective To evaluate the incidence, trends, seasonality, and age at the time of
hepatoportoenterostomy (Kasai procedure) for biliary atresia in the US. Study design The …
hepatoportoenterostomy (Kasai procedure) for biliary atresia in the US. Study design The …
Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-γ in experimental biliary atresia
P Shivakumar, KM Campbell, GE Sabla… - The Journal of …, 2004 - Am Soc Clin Investig
The etiology and pathogenesis of bile duct obstruction in children with biliary atresia are
largely unknown. We have previously reported that, despite phenotypic heterogeneity …
largely unknown. We have previously reported that, despite phenotypic heterogeneity …
Biliary atresia: clinical profiles, risk factors, and outcomes of 755 patients listed for liver transplantation
EC Utterson, RW Shepherd, RJ Sokol… - The Journal of …, 2005 - Elsevier
OBJECTIVES: To test the hypothesis that risk analysis from the time of listing for liver
transplantation (LT) focuses attention on areas where outcomes can be improved. STUDY …
transplantation (LT) focuses attention on areas where outcomes can be improved. STUDY …