[HTML][HTML] Epstein–Barr virus in multiple sclerosis: theory and emerging immunotherapies
New treatments for multiple sclerosis (MS) focused on B cells have created an atmosphere
of excitement in the MS community. B cells are now known to play a major role in disease …
of excitement in the MS community. B cells are now known to play a major role in disease …
[HTML][HTML] Epstein–Barr virus epidemiology, serology, and genetic variability of LMP-1 oncogene among healthy population: an update
The Epstein–Barr virus (EBV) is a DNA lymphotropic herpesvirus and the causative agent of
infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of …
infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of …
Epstein-Barr virus as a cause of multiple sclerosis: opportunities for prevention and therapy
F Aloisi, G Giovannoni, M Salvetti - The Lancet Neurology, 2023 - thelancet.com
Multiple sclerosis is a chronic inflammatory disease of the CNS that results from the interplay
between heritable and environmental factors. Mounting evidence from different fields of …
between heritable and environmental factors. Mounting evidence from different fields of …
[HTML][HTML] Role of viruses in the pathogenesis of multiple sclerosis
RE Tarlinton, E Martynova, AA Rizvanov… - Viruses, 2020 - mdpi.com
Multiple sclerosis (MS) is an immune inflammatory disease, where the underlying etiological
cause remains elusive. Multiple triggering factors have been suggested, including …
cause remains elusive. Multiple triggering factors have been suggested, including …
[HTML][HTML] The CD8 T cell-Epstein-Barr virus-B cell trialogue: a central issue in multiple sclerosis pathogenesis
C Veroni, F Aloisi - Frontiers in immunology, 2021 - frontiersin.org
The cause and the pathogenic mechanisms leading to multiple sclerosis (MS), a chronic
inflammatory disease of the central nervous system (CNS), are still under scrutiny. During …
inflammatory disease of the central nervous system (CNS), are still under scrutiny. During …
Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis
S Abrahamyan, B Eberspächer, MM Hoshi… - Journal of Neurology …, 2020 - jnnp.bmj.com
Objective To determine the prevalence of antibodies to Epstein-Barr virus (EBV) in a large
cohort of patients with early multiple sclerosis (MS). Methods Serum samples were collected …
cohort of patients with early multiple sclerosis (MS). Methods Serum samples were collected …
The role of Epstein-Barr virus in the etiology of multiple sclerosis: a current review
K Ruprecht - Expert review of clinical immunology, 2020 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system. While its exact etiology is unknown, it is generally believed that MS …
central nervous system. While its exact etiology is unknown, it is generally believed that MS …
Role of environmental factors in multiple sclerosis
A Zarghami, Y Li, SB Claflin, I van der Mei… - Expert Review of …, 2021 - Taylor & Francis
Introduction Environmental factors play a significant role in the pathogenesis and
progression of multiple sclerosis (MS), either acting alone or by interacting with other …
progression of multiple sclerosis (MS), either acting alone or by interacting with other …
Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis
C Pfuhl, U Grittner, RM Gieß, M Scheel, JR Behrens… - Neurology, 2019 - AAN Enterprises
Objectives To evaluate intrathecal immunoglobulin M (IgM) production, as compared to
previously established risk factors, as risk factor for conversion from clinically isolated …
previously established risk factors, as risk factor for conversion from clinically isolated …
[HTML][HTML] Epstein-Barr Virus and multiple sclerosis in a Spanish cohort: A two-years longitudinal study
MI Domínguez-Mozo, L López-Lozano… - Frontiers in …, 2022 - frontiersin.org
Objectives 1. To analyze the prevalence and levels of anti-EBNA-1 and anti-VCA IgG
antibodies of Epstein-Barr virus (EBV) in a Spanish cohort of multiple sclerosis (MS) patients …
antibodies of Epstein-Barr virus (EBV) in a Spanish cohort of multiple sclerosis (MS) patients …