Temozolomide in the era of precision medicine
A Thomas, M Tanaka, J Trepel, WC Reinhold… - Cancer research, 2017 - AACR
Abstract In the January 1, 2017, issue of Cancer Research, Nagel and colleagues
demonstrate the value of assays that determine the DNA repair capacity of cancers in …
demonstrate the value of assays that determine the DNA repair capacity of cancers in …
[HTML][HTML] Stereotactic radiosurgery (SRS) in the modern management of patients with brain metastases
Stereotactic radiosurgery (SRS) is an established non-invasive ablative therapy for brain
metastases. Early clinical trials with SRS proved that tumor control rates are superior to …
metastases. Early clinical trials with SRS proved that tumor control rates are superior to …
Preclinical and clinical efficacy of trastuzumab deruxtecan in breast cancer brain metastases
Purpose: Brain metastases can occur in up to 50% of patients with metastatic HER2-positive
breast cancer. Because patients with active brain metastases were excluded from previous …
breast cancer. Because patients with active brain metastases were excluded from previous …
Linac-based VMAT radiosurgery for multiple brain lesions: comparison between a conventional multi-isocenter approach and a new dedicated mono-isocenter …
R Ruggieri, S Naccarato, R Mazzola, F Ricchetti… - Radiation …, 2018 - Springer
Background Linac-based stereotactic radiosurgery or fractionated stereotactic radiotherapy
(SRS/FSRT) of multiple brain lesions using volumetric modulated arc therapy (VMAT) is …
(SRS/FSRT) of multiple brain lesions using volumetric modulated arc therapy (VMAT) is …
Treatment strategies for low-grade glioma in adults
NA Oberheim Bush, S Chang - Journal of oncology practice, 2016 - ascopubs.org
Diffuse low-grade gliomas include oligodendrogliomas and astrocytomas. The recent 2016
WHO classification has now updated the definition of these tumors to include molecular …
WHO classification has now updated the definition of these tumors to include molecular …
Stereotactic radiosurgery alone for multiple brain metastases? A review of clinical and technical issues
Over the past three decades several randomized trials have enabled evidence-based
practice for patients presenting with limited brain metastases. These trials have focused on …
practice for patients presenting with limited brain metastases. These trials have focused on …
Neurosurgical management of patients with brain metastasis
Brain metastasis is a serious complication in patients with systemic cancer. The main goal of
the treatment in patients with brain metastasis is to control the disease in the brain, to …
the treatment in patients with brain metastasis is to control the disease in the brain, to …
Diagnostic accuracy of PET for differentiating true glioma progression from post treatment-related changes: a systematic review and meta-analysis
M Cui, RI Zorrilla-Veloz, J Hu, B Guan, X Ma - Frontiers in Neurology, 2021 - frontiersin.org
Purpose: To evaluate the diagnostic accuracy of PET with different radiotracers and
parameters in differentiating between true glioma progression (TPR) and post treatment …
parameters in differentiating between true glioma progression (TPR) and post treatment …
Drug resistance in HER2-positive breast cancer brain metastases: blame the barrier or the brain?
The brain is the most common site of first metastasis for patients with HER2-positive breast
cancer treated with HER2-targeting drugs. However, the development of effective therapies …
cancer treated with HER2-targeting drugs. However, the development of effective therapies …
Tumor‐targeted nanotherapeutics: overcoming treatment barriers for glioblastoma
AS Wadajkar, JG Dancy, DS Hersh… - Wiley …, 2017 - Wiley Online Library
Glioblastoma (GBM) is a highly aggressive and lethal form of primary brain cancer.
Numerous barriers exist to the effective treatment of GBM including the tightly controlled …
Numerous barriers exist to the effective treatment of GBM including the tightly controlled …