[HTML][HTML] Antibacterial gas therapy: strategies, advances, and prospects

TY Wang, XY Zhu, FG Wu - Bioactive Materials, 2023 - Elsevier
One of the challenges posed by current antibacterial therapy is that the expanded and
massive use of antibiotics endows bacteria with the ability to resist almost all kinds of …

Recent advances in self-immolative linkers and their applications in polymeric reporting systems

AG Gavriel, MR Sambrook, AT Russell, W Hayes - Polymer Chemistry, 2022 - pubs.rsc.org
Interest in self-immolative chemistry has grown over the past decade with more research
groups harnessing the versatility to control the release of a compound from a larger …

Development and Application of Carbonyl Sulfide-Based Donors for H2S Delivery

CM Levinn, MM Cerda, MD Pluth - Accounts of chemical research, 2019 - ACS Publications
Conspectus In addition to nitric oxide and carbon monoxide, hydrogen sulfide (H2S) has
been recently recognized as an important biological signaling molecule with implications in …

External stimuli-responsive gasotransmitter prodrugs: Chemistry and spatiotemporal release

X Ji, Z Zhong - Journal of Controlled Release, 2022 - Elsevier
Gasotransmitters like nitric oxide, carbon monoxide, and hydrogen sulfide with unique
pleiotropic pharmacological effects in mammals are an emerging therapeutic modality for …

Activatable small-molecule hydrogen sulfide donors

CM Levinn, MM Cerda, MD Pluth - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: Hydrogen sulfide (H2S) is an important biological signaling molecule involved
in many physiological processes. These diverse roles have led researchers to develop …

The path to controlled delivery of reactive sulfur species

X Ni, SS Kelly, S Xu, M Xian - Accounts of Chemical Research, 2021 - ACS Publications
Conspectus Reactive sulfur species (RSS) play regulatory roles in many physiological and
pathological processes. Since the discovery of hydrogen sulfide (H2S) as a nitric oxide (NO) …

H2S and reactive sulfur signaling at the host-bacterial pathogen interface

BJC Walsh, DP Giedroc - Journal of Biological Chemistry, 2020 - ASBMB
Bacterial pathogens that cause invasive disease in the vertebrate host must adapt to host
efforts to cripple their viability. Major host insults are reactive oxygen and reactive nitrogen …

Fluorogenic hydrogen sulfide (H 2 S) donors based on sulfenyl thiocarbonates enable H 2 S tracking and quantification

Y Zhao, MM Cerda, MD Pluth - Chemical Science, 2019 - pubs.rsc.org
Hydrogen sulfide (H2S) is an important cellular signaling molecule that exhibits promising
protective effects. Although a number of triggerable H2S donors have been developed …

An ROS-Responsive Donor That Self-Reports Its H2S Delivery by Forming a Benzoxazole-Based Fluorophore

Q Hu, C Zhu, RA Hankins, AR Murmello… - Journal of the …, 2023 - ACS Publications
Hydrogen sulfide (H2S), an endogenous signaling molecule, is known to play a pivotal role
in neuroprotection, vasodilation, and hormonal regulation. To further explore the biological …

Single-Component Photo-Responsive Template for the Controlled Release of NO and H2S2

B Roy, M Shieh, S Xu, X Ni, M Xian - Journal of the American …, 2022 - ACS Publications
Redox signaling molecules include a number of reactive oxygen species (ROS), reactive
nitrogen species (RNS), and reactive sulfur species (RSS). These molecules work …