Recent advances in point-of-care testing of COVID-19

S Lee, L Bi, H Chen, D Lin, R Mei, Y Wu… - Chemical Society …, 2023 - pubs.rsc.org
Advances in microfluidic device miniaturization and system integration contribute to the
development of portable, handheld, and smartphone-compatible devices. These …

Designing nanotheranostics with machine learning

L Rao, Y Yuan, X Shen, G Yu, X Chen - Nature Nanotechnology, 2024 - nature.com
The inherent limits of traditional diagnoses and therapies have driven the development and
application of emerging nanotechnologies for more effective and safer management of …

Affinity exploration of SARS-CoV-2 RBD variants to mAb-functionalized plasmonic metasurfaces for label-free immunoassay boosting

F Li, J Hong, C Guan, K Chen, Y Xie, Q Wu, J Chen… - ACS …, 2023 - ACS Publications
Plasmonic metasurfaces (PMs) functionalized with the monoclonal antibody (mAb) are
promising biophotonic sensors for biomolecular interaction analysis and convenient …

Digital detection of proteins

DC Duffy - Lab on a Chip, 2023 - pubs.rsc.org
This paper reviews methods for detecting proteins based on molecular digitization, ie, the
isolation and detection of single protein molecules or singulated ensembles of protein …

Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19

H Yuan, P Chen, C Wan, Y Li, BF Liu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Abstract The Coronavirus disease 2019 (COVID-19) outbreak has urged the establishment
of a global-wide rapid diagnostic system. Current widely-used tests for COVID-19 include …

The application of nanoparticles in point-of-care testing (POCT) immunoassays

F Hou, S Sun, SW Abdullah, Y Tang, X Li, H Guo - Analytical Methods, 2023 - pubs.rsc.org
The Covid-19 pandemic has led to greater recognition of the importance of the fast and
timely detection of pathogens. Recent advances in point-of-care testing (POCT) technology …

Explanatory predictive model for COVID-19 severity risk employing machine learning, shapley addition, and LIME

M Laatifi, S Douzi, H Ezzine, CE Asry, A Naya… - Scientific Reports, 2023 - nature.com
The rapid spread of SARS-CoV-2 threatens global public health and impedes the operation
of healthcare systems. Several studies have been conducted to confirm SARS-CoV-2 …

A review on recent advances of AI-integrated microfluidics for analytical and bioanalytical applications

E Asadian, F Bahramian, S Siavashy… - TrAC Trends in …, 2024 - Elsevier
In today's biomedical research, the pursuit of diagnostic tools boasting maximum precision
and accuracy while minimizing sample volume and pre-treatment requirements, has …

An electrochemical paper-based hydrogel immunosensor to monitor serum cytokine for predicting the severity of COVID-19 patients

D Shi, C Zhang, X Li, J Yuan - Biosensors and Bioelectronics, 2023 - Elsevier
Abstract Analysis of cytokines levels in human serum is critical as it can be a “symptom
diagnostic biomarker” in COVID-19, giving real-time information about human health status …

Microfluidics technology in SARS-CoV-2 diagnosis and beyond: a systematic review

MR Jamiruddin, BA Meghla, DZ Islam, TA Tisha… - Life, 2022 - mdpi.com
With the progression of the COVID-19 pandemic, new technologies are being implemented
for more rapid, scalable, and sensitive diagnostics. The implementation of microfluidic …