Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

With the rapid development of nanotechnology as well as growing interest in
immunotherapy, a great number of vaccine delivery vehicles have been explored in order to …

Vaccination is an innovative strategy for cancer treatment by leveraging various components
of the patients' immunity to boost an anti-tumor immune response. Rationally designed …

Poly-γ-glutamic acid (γ-PGA) is a naturally occurring biopolymer made up of repeating units
of l-glutamic acid, d-glutamic acid or both. γ-PGA can exhibit different properties …

Advantages of polymeric nanoparticles as drug delivery systems include controlled release,
enhanced drug stability and bioavailability, and specific tissue targeting. Nanoparticle …

Glaucoma is a leading cause of irreversible visual impairment and blindness, affecting over
76.0 million people worldwide in 2020, with a predicted increase to 111.8 million by 2040 …

Microbial biopolymers have emerged as promising solutions for environmental pollution-
related human health issues. Poly-γ-glutamic acid (γ-PGA), a natural anionic polymeric …

The development of intravitreal glucocorticoid delivery systems is a current global challenge
for the treatment of inflammatory diseases of the posterior segment of the eye. The main …

Highlights•Intravitreal nanoparticles are promising to facilitate retinal delivery.•Size, charge,
stability and ligand choice are important for delivery efficiency.•Combined parameters are …

Immunosuppression with glucocorticoids is a common treatment for autoimmune liver
diseases and after liver transplant, which is however associated with severe side-effects …