Tissue engineered skin substitutes

P Goodarzi, K Falahzadeh, M Nematizadeh… - Cell Biology and …, 2018 - Springer
The fundamental skin role is to supply a supportive barrier to protect body against harmful
agents and injuries. Three layers of skin including epidermis, dermis and hypodermis form a …

From grafts to human bioengineered vascularized skin substitutes

W Oualla-Bachiri, A Fernández-González… - International journal of …, 2020 - mdpi.com
The skin plays an important role in the maintenance of the human's body physiological
homeostasis. It acts as a coverage that protects against infective microorganism or …

Neutrophil dysfunction, immature granulocytes, and cell-free DNA are early biomarkers of sepsis in burn-injured patients: a prospective observational cohort study

P Hampson, RJ Dinsdale, CM Wearn… - Annals of …, 2017 - journals.lww.com
Objective: The aim of this study was to measure neutrophil function longitudinally following
burn injury and to examine the relationship between neutrophil dysfunction and sepsis …

In vivo efficacy of single phage versus phage cocktail in resolving burn wound infection in BALB/c mice

P Chadha, OP Katare, S Chhibber - Microbial pathogenesis, 2016 - Elsevier
Klebsiella pneumoniae is one of the most predominant pathogens associated with burn
wound infections, causing considerable morbidity and mortality. The indiscriminate usage of …

Methodologies in creating skin substitutes

MN Nicholas, MG Jeschke, S Amini-Nik - Cellular and molecular life …, 2016 - Springer
The creation of skin substitutes has significantly decreased morbidity and mortality of skin
wounds. Although there are still a number of disadvantages of currently available skin …

Effect of parenteral selenium supplementation in critically ill patients: a systematic review and meta-analysis

TS Huang, YC Shyu, HY Chen, LM Lin, CY Lo… - PloS one, 2013 - journals.plos.org
Background It is currently unclear whether parenteral selenium supplementation should be
recommended in the management of critically ill patients. Here we conducted a systematic …

[HTML][HTML] Coagulopathy and its management in patients with severe burns

GJ Glas, M Levi, MJ Schultz - Journal of Thrombosis and Haemostasis, 2016 - Elsevier
Severe burn injury is associated with systemic coagulopathy. The changes in coagulation
described in patients with severe burns resemble those found patients with sepsis or major …

Late immune consequences of combat trauma: a review of trauma-related immune dysfunction and potential therapies

KB Thompson, LT Krispinsky, RJ Stark - Military Medical Research, 2019 - Springer
With improvements in personnel and vehicular body armor, robust casualty evacuation
capabilities, and damage control resuscitation strategies, more combat casualties are …

The utility of procalcitonin in critically ill trauma patients

JV Sakran, CP Michetti, MJ Sheridan… - Journal of Trauma …, 2012 - journals.lww.com
BACKGROUND Procalcitonin (PCT), the prohormone of calcitonin, has an early and highly
specific increase in response to systemic bacterial infection. The objectives of this study …

The prognostic value of serum procalcitonin measurements in critically injured patients: a systematic review

AN AlRawahi, FA AlHinai, CJ Doig, CG Ball, E Dixon… - Critical Care, 2019 - Springer
Background Major trauma is associated with high incidence of septic complications and
multiple organ dysfunction (MOD), which markedly influence the outcome of injured patients …