Macrophages derived from human induced pluripotent stem cells (iPSCs) have the potential
to enable the development of cell-based therapies for numerous disease conditions. We …

The generation of hematopoietic stem cells (HSCs) from induced pluripotent stem cells
(iPSCs) is an active and promising area of research; however, generating engraftable HSCs …

During the last years, several strategies have been made to obtain mature erythrocytes or
red blood cells (RBC) from the bone marrow or umbilical cord blood (UCB). However, UCB …

Parasites of the genus Plasmodium that cause malaria survive within humans by invasion of,
and proliferation within, the most abundant cell type in the body, the red blood cell. As …

Red blood cell (RBC) transfusion is a lifesaving medical procedure that can treat patients
with anemia and hemoglobin disorders. However, the shortage of blood supply and risks of …

Patients with inherited anemia and hemoglobinopathies (such as sickle cell disease and β-
thalassemia) are treated with red blood cell (RBC) transfusions to alleviate their symptoms …

Recently, Isiksacan et al. introduced in their perspective article the assessment of stored red
blood cells (RBCs) through lab-ona-chip (LOC) technologies for precision transfusion …

Background Human induced pluripotent stem cells (hiPSCs) offer a renewable source of
cells for the generation of hematopoietic cells for cell-based therapy, disease modeling, and …

Biphosphoglycerate mutase (BPGM) is a tri-functional enzyme expressed exclusively in
erythroid cells and tissues that is responsible for the production of 2, 3-biphosphoglycerate …

Amidst the global shortfalls in blood supply, storage limitations of donor blood and the
availability of potential blood substitutes for transfusion applications, society has pivoted …