The rise of PSMA ligands for diagnosis and therapy of prostate cancer

A Afshar-Oromieh, JW Babich… - Journal of Nuclear …, 2016 - Soc Nuclear Med
The prostate-specific membrane antigen (PSMA) has received increased consideration
during the past few years as an excellent target for both imaging and therapy of prostate …

68Ga-PSMA ligand PET/CT in patients with prostate cancer: How we review and report

I Rauscher, T Maurer, WP Fendler, WH Sommer… - Cancer Imaging, 2016 - Springer
Recently, positron emission tomography (PET) imaging using PSMA-ligands has gained
high attention as a promising new radiotracer in patients with prostate cancer (PC). Several …

Multisite Experience of the Safety, Detection Rate and Diagnostic Performance of Fluciclovine (18F) Positron Emission Tomography/Computerized Tomography …

T Bach-Gansmo, C Nanni, PT Nieh, L Zanoni… - The Journal of …, 2017 - auajournals.org
Purpose: Sensitive detection of cancer foci in men experiencing biochemical recurrence
following initial treatment of prostate cancer is of great clinical significance with a possible …

18F-DCFBC PET/CT for PSMA-based detection and characterization of primary prostate cancer

SP Rowe, KL Gage, SF Faraj, KJ Macura… - Journal of Nuclear …, 2015 - Soc Nuclear Med
We previously demonstrated the ability to detect metastatic prostate cancer using N-[N-[(S)-
1, 3-dicarboxypropyl] carbamoyl]-4-18F-fluorobenzyl-l-cysteine (18F-DCFBC), a low …

Anti-3-[18F]FACBC Positron Emission Tomography-Computerized Tomography and 111In-Capromab Pendetide Single Photon Emission Computerized …

DM Schuster, PT Nieh, AB Jani, R Amzat… - The Journal of …, 2014 - auajournals.org
Purpose: We prospectively evaluated the amino acid analogue positron emission
tomography radiotracer anti-3-[18F] FACBC compared to ProstaScint®(111In-capromab …

Recurrent prostate cancer detection with anti-3-[18F]FACBC PET/CT: comparison with CT

OA Odewole, FI Tade, PT Nieh, B Savir-Baruch… - European journal of …, 2016 - Springer
Purpose To compare the diagnostic performance of the synthetic amino acid analogue PET
radiotracer anti-3-[18 F] FACBC (fluciclovine) with that of CT in the detection of recurrent …

Update on 18F-fluciclovine PET for prostate cancer imaging

EE Parent, DM Schuster - Journal of Nuclear Medicine, 2018 - Soc Nuclear Med
PET is a functional imaging method that can exploit various aspects of tumor biology to
enable greater detection of prostate cancer than can be provided by morphologic imaging …

A review of imaging methods for prostate cancer detection: supplementary issue: image and video acquisition and processing for clinical applications

S Sarkar, S Das - Biomedical engineering and computational …, 2016 - journals.sagepub.com
Imaging is playing an increasingly important role in the detection of prostate cancer (PCa).
This review summarizes the key imaging modalities–multiparametric ultrasound (US) …

Localized Prostate Cancer Detection with 18F FACBC PET/CT: Comparison with MR Imaging and Histopathologic Analysis

B Turkbey, E Mena, J Shih, PA Pinto, MJ Merino… - Radiology, 2014 - pubs.rsna.org
Purpose To characterize uptake of 1-amino-3-fluorine 18-fluorocyclobutane-1-carboxylic
acid (18F FACBC) in patients with localized prostate cancer, benign prostatic hyperplasia …

Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid: physiologic uptake patterns, incidental findings, and variants that may simulate disease

DM Schuster, C Nanni, S Fanti, S Oka… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid (18F-FACBC) is a synthetic amino
acid analog PET radiotracer undergoing clinical trials for the evaluation of prostate and other …