The transmembrane glycoprotein mucin 1 (MUC1) is a mucin family member that has
different functions in normal and cancer cells. Owing to its structural and biochemical …

Mucins—large extracellular proteins that are heavily glycosylated with complex
oligosaccharides—establish a selective molecular barrier at the epithelial surface and …

Mucosal surfaces line our body cavities and provide the interaction surface between
commensal and pathogenic microbiota and the host. The barrier function of the mucosal …

Abstract Mucin 1 (MUC1) is a heterodimeric protein formed by two subunits that is aberrantly
overexpressed in human breast cancer and other cancers. Historically, much of the early …

Cell surface mucins are large transmembrane glycoproteins involved in diverse functions
ranging from shielding the airway epithelium against pathogenic infection to regulating …

Mucins are the main structural components of mucus that create a selective protective
barrier for epithelial surface and also execute wide range of other physiological functions …

Mucins (MUC) are high molecular weight O-linked glycoproteins whose primary functions
are to hydrate, protect, and lubricate the epithelial luminal surfaces of the ducts within the …

Cell surface mucin glycoproteins are highly expressed by all mucosal tissues, yet their
physiological role is currently unknown. We hypothesized that cell surface mucins protect …

The mucin (MUC) family is a group of highly glycosylated macromolecules that are
abundantly expressed in mammalian epithelial cells. MUC proteins contribute to the …

Mucins are heavily glycosylated high molecular weight glycoproteins, which are involved in
the protection and lubrication of luminal epithelial surfaces. Transmembrane mucins also …