Cancer is a major public health problem worldwide with more than an estimated 19.3 million
new cases in 2020. The occurrence rises dramatically with age, and the overall risk …

The role of cyclins in hormone-dependent neoplasms is crucial in the development of the
disease that is resistant to first-line therapy, as the example of breast cancer shows …

Human milk oligosaccharides (HMO) are considered to influence the composition of the gut
microflora in breastfed infants. We investigated direct effects of milk HMO fractions or …

Background Prostate cancer (PCa) is a common malignancy occurring in men. As both an
endocrine and gonadal organ, prostate is closely correlated with androgen. So, androgen …

High grade serous ovarian cancer (HGSOC) is a fatal gynecologic malignancy in the US
with limited treatment options. New therapeutic strategies include targeting of the cell cycle …

Prostate cancer (PCa) is a common urinary malignancy. The lack of specific and sensitive
biomarkers for the early diagnosis and prognosis of PCa makes it important to seek …

Cyclin B1 is a key mitotic cyclin in the G2-M phase transition of the cell cycle and is
overexpressed in various malignant tumors. Numerous studies have reported contradictory …

Abstract Background and Purpose Prostate cancer remains a major public health burden
worldwide. Polo like kinase 4 (PLK4) has emerged as a promising therapeutic target in …

Head and neck cancer (HNC) therapy is limited; therefore, new solutions are increasingly
being sought among flavonoids, which exhibit numerous biological properties, including …

Prostate cancer (PCa) is one of the most frequently diagnosed cancers among men in the
world. Its prevention has been limited because of an incomplete understanding of how …