Possibly of all the common phospholipids, least is known about plasmalogens. Although
plasmalogens represent one in every five phospholipids in the human body, one would be …

Phospholipase A 2 s are enzymes that hydrolyze the fatty acid at the sn-2 position of the
glycerol backbone of membrane glycerophospholipids. Given the asymmetric distribution of …

Over one hundred different phospholipid molecular species are known to be present in
mammalian cells and tissues. Fatty acid remodeling systems for phospholipids including …

Prostanoids are local hormones formed from arachidonic acid that coordinate responses to
circulating hormones which elicit prostanoid synthesis. For example, in the kidney …

The development of mass spectrometry-based techniques is opening new insights into the
understanding of arachidonic acid (AA) metabolism. AA incorporation, remodeling and …

Leukotrienes are metabolites of arachidonic acid derived from the action of 5-LO (5-
lipoxygenase). The immediate product of 5-LO is LTA4 (leukotriene A4), which is …

Over 100 different phospholipid molecular species are known to be present in mammalian
cells and tissues. Fatty acid remodeling systems for phospholipids including acyl-CoA …

Collision-induced dissociation (CID) of the [M+ H]+ of glycerophospholipids typically results
in abundant fragment ions that are related to the polar head group or loss of the polar head …

Numerous studies have indicated that the fatty acids of cellular phospholipids are distributed
asymmetrically. In general, saturated fatty acids are esterified at the sn-1 position while …

The cycle of deacylation and reacylation of phospholipids plays a critical role in regulating
availability of arachidonic acid for eicosanoid production. The major yeast lysophospholipid …