Abstract β‐Phenyl‐γ‐aminobutyric acid (phenibut) is an analog of the inhibitory
neurotransmitter γ‐aminobutyric acid (GABA) that was first synthesized in Russia in the early …

Phenibut is a glutamic acid derivative with activity on the γ-aminobutyric acid (GABA) B, A,
and B-phenethylamine receptors. It is prescribed in former Communist Bloc countries for …

Background: Originally believed to be an atypical antidepressant acting at serotonin
transporters, tianeptine is now known to also be an atypical agonist at mu-opioid receptors …

There are many nonopioid central nervous system depressant substances that share a
gamma‐aminobutyric acid (GABA) receptor–related mechanism of action. These sedatives …

Phenibut is a nootropic drug that exerts anxiolytic and antinociceptive effects by acting on
the GABA B receptor and the α 2-δ subunit of voltage-dependent calcium channels. An …

Abstract Purpose of Review Phenibut (β-phenyl-γ-aminobutyric acid) is a psychoactive
GABA analogue currently being marketed online as an anxiolytic and nootropic dietary …

Discussion This case illustrates the misuse and abuse potential of phenibut, an anxiolytic
marketed for use in Russia and Ukraine that is structurally similar to baclofen and γ …

Objectives This systematic review aimed to identify published articles that evaluated all
phenibut toxicity and withdrawal cases to understand better their clinical presentations and …

Objective Phenibut is a widely available gamma-aminobutyric acid B receptor agonist. When
taken chronically, phenibut causes dependence and subsequent withdrawal if stopped …

Introduction Phenibut is an unregulated supplement that acts primarily as a gamma-
aminobutyric acid type B receptor agonist. Use of phenibut can lead to dependence and …