Traumatic spinal cord injury results in severe and irreversible loss of function. The injury
triggers a complex cascade of inflammatory and pathological processes, culminating in …

Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

The neurone-centred view of the past disregarded or downplayed the role of astroglia as a
primary component in the pathogenesis of neurological diseases. As this concept is …

Astrocytes sense changes in neural activity and extracellular space composition. In
response, they exert homeostatic mechanisms critical for maintaining neural circuit function …

Glial fibrillary acidic protein (GFAP) is the hallmark intermediate filament (IF; also known as
nanofilament) protein in astrocytes, a main type of glial cells in the central nervous system …

Astrocytes are the most abundant cells in the central nervous system (CNS) that provide
nutrients, recycle neurotransmitters, as well as fulfill a wide range of other homeostasis …

Astrocytes are the most abundant cell type within the central nervous system. They play
essential roles in maintaining normal brain function, as they are a critical structural and …

Traumatic brain injury (TBI) represents a major cause of death and disability in developed
countries. Brain injuries are highly heterogeneous and can also trigger other neurological …

Astrocyte activation and reactive gliosis accompany most of the pathologies in the brain,
spinal cord, and retina. Reactive gliosis has been described as constitutive, graded, multi …

Brain circuits undergo substantial structural changes during development, driven by the
formation, stabilization, and elimination of synapses. Synaptic connections continue to …