Lyme disease pathogenesis
Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …
The emergence of Lyme disease
AC Steere, J Coburn, L Glickstein - The Journal of clinical …, 2004 - Am Soc Clin Investig
Since its identification nearly 30 years ago, Lyme disease has continued to spread, and
there have been increasing numbers of cases in the northeastern and north central US. The …
there have been increasing numbers of cases in the northeastern and north central US. The …
Profiling of Temperature-Induced Changes in Borrelia burgdorferi Gene Expression by Using Whole Genome Arrays
C Ojaimi, C Brooks, S Casjens, P Rosa… - Infection and …, 2003 - Am Soc Microbiol
Borrelia burgdorferi is the etiologic agent of Lyme disease, the most prevalent arthropod-
borne disease in the United States. The genome of the type strain, B31, consists of a …
borne disease in the United States. The genome of the type strain, B31, consists of a …
The role of Borrelia burgdorferi outer surface proteins
MR Kenedy, TR Lenhart… - FEMS Immunology & …, 2012 - academic.oup.com
Human pathogenic spirochetes causing Lyme disease belong to the Borrelia burgdorferi
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …
A plasmid‐encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host
JE Purser, MB Lawrenz, MJ Caimano… - Molecular …, 2003 - Wiley Online Library
Borrelia burgdorferi, a spirochaete that causes Lyme borreliosis, contains 21 linear and
circular plasmids thought to be important for survival in mammals or ticks. Our results …
circular plasmids thought to be important for survival in mammals or ticks. Our results …
Elucidation of Lyme arthritis
AC Steere, L Glickstein - Nature Reviews Immunology, 2004 - nature.com
Before the first description of Lyme arthritis in 1976, patients with this disease were often
thought to have juvenile or adult rheumatoid arthritis. It is now known that Lyme arthritis is …
thought to have juvenile or adult rheumatoid arthritis. It is now known that Lyme arthritis is …
Global Analysis of Borrelia burgdorferi Genes Regulated by Mammalian Host-Specific Signals
Lyme disease is a tick-borne infection that can lead to chronic, debilitating problems if not
recognized or treated appropriately. Borrelia burgdorferi, the causative agent of Lyme …
recognized or treated appropriately. Borrelia burgdorferi, the causative agent of Lyme …
Combined Effects of Blood and Temperature Shift on Borrelia burgdorferi Gene Expression as Determined by Whole Genome DNA Array
R Tokarz, JM Anderton, LI Katona… - Infection and …, 2004 - Am Soc Microbiol
Borrelia burgdorferi undergoes differential gene expression during transmission from its tick
vector to a vertebrate host. The addition of blood to a spirochete culture at 35° C for 48 h had …
vector to a vertebrate host. The addition of blood to a spirochete culture at 35° C for 48 h had …
Stage‐specific global alterations in the transcriptomes of L yme disease spirochetes during tick feeding and following mammalian host adaptation
R Iyer, MJ Caimano, A Luthra, D Axline Jr… - Molecular …, 2015 - Wiley Online Library
B orrelia burgdorferi, the agent of L yme disease, is maintained in nature within an enzootic
cycle involving a mammalian reservoir and an I xodes sp. tick vector. The transmission …
cycle involving a mammalian reservoir and an I xodes sp. tick vector. The transmission …
Complement evasion strategies of Borrelia burgdorferi sensu lato
V Dulipati, S Meri, J Panelius - FEBS letters, 2020 - Wiley Online Library
Borreliosis (Lyme disease) is a spirochetal disease caused by the species complex of
Borrelia burgdorferi transmitted by Ixodes spp. ticks. Recorded to be the most common tick …
Borrelia burgdorferi transmitted by Ixodes spp. ticks. Recorded to be the most common tick …