Asthma is chronic inflammation of the airways characterized by airway hyper-
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …

Interleukins (IL)-4 and-13 play a pivotal role in the pathobiology of type-2 asthma. Indeed, IL-
4 is crucially involved in Th2 cell differentiation, immunoglobulin (Ig) class switching and …

Asthma is a high-prevalence disease, still accounting for mortality and high direct and
indirect costs. It is now recognized that, despite the implementation of guidelines, a large …

Asthma is a disease of reversible airflow obstruction characterised clinically by wheezing,
shortness of breath, and coughing. Increases in airway type 2 cytokine activity, including …

The Human Mesenchymal Stem Cell (hMSC) secretome has pleiotropic effects
underpinning its therapeutic potential. hMSC serum-free conditioned media (SFCM) …

Asthma is a common disease affecting 350 million people worldwide, which is characterized
by airways inflammation and hyperreactivity. Historically diagnosis and treatment have been …

abstract Interleukin (IL)-4 and IL-13, signature type 2 cytokines, exert their actions by binding
to two types of receptors sharing the IL-4R a chain (IL-4Ra). Since IL-4 and IL-13 play …

Asthma is a heterogeneous chronic inflammatory disease of the airways that affects
approximately 300 million people worldwide. About 5–10% of all asthmatics suffer from …

The heterogeneous nature of asthma has been understood for decades, but the precise
categorization of asthma has taken on new clinical importance in the era of specific biologic …

Cutaneous T-cell lymphomas (CTCLs) primarily affect skin and are characterized by
proliferation of mature CD4+ T-helper cells. The pattern of cytokine production in the skin …